Publications by authors named "Tasneem Drie"

Article Synopsis
  • Uveitis is a common complication in about 23% of ankylosing spondylitis patients, posing significant treatment challenges.
  • A 32-year-old male who had recurrent anterior uveitis and inflammatory back pain was eventually diagnosed with ankylosing spondylitis and found clinical remission after starting Golimumab.
  • Clinical guidelines support using drugs like etanercept and adalimumab for recurrent uveitis in ankylosing spondylitis, but Golimumab has also shown effectiveness in difficult cases resistant to other treatments.
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Introduction: Multiple myeloma (MM) is a malignant plasma cell proliferation producing large numbers of monoclonal immunoglobulins. Typical MM symptoms include anemia, bone pain, hypercalcemia, and renal failure. Atypical presentations like joint involvement were rarely reported in the literature and may cause significant delays in treatment and adverse outcomes.

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Introduction: Systemic lupus erythematosus (SLE) is a systemic immune disease that classically occurs in young to middle-aged women and may present with cutaneous, renal, haematologic, neurological, and/or other symptoms at the time of diagnosis. Late-onset SLE or SLE in the elderly is a subtype that differs from classic SLE in terms of age group, clinical symptoms, organ involvement and severity.

Case Presentation: A 63-year-old female noted to have pancytopenia.

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Introduction And Importance: The use of cyclophosphamide in women of childbearing age with severe systemic lupus erythematosus is normally indicated. However, cyclophosphamide is generally avoided during pregnancy due to the risk of teratogenicity, especially since its effect on fetal survival is poorly understood. This is a case report of a lupus patient exposed to cyclophosphamide during pregnancy.

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Introduction And Importance: Rhupus syndrome is a very rare combination of systemic lupus erythematosus and rheumatoid arthritis. It is characterized by the presence of erosive arthritis with symptoms and signs of systemic lupus erythematosus. Rheumatoid nodules and neurological and renal involvement are further complications of Rhupus syndrome, leading to a worse prognosis.

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Introduction: Systemic lupus erythematosus (SLE) is a systemic disease, with unknown etiology. The authors aimed in this study to determine the connection between mean platelet volume (MPV) and disease activity of SLE. Although it has been studied in other rheumatological conditions like rheumatoid arthritis, its role in adult patients with SLE needs to be defined, especially in Syria.

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Article Synopsis
  • Diagnosing sarcoidosis alongside Sjögren's syndrome (SS) is difficult because sarcoidosis typically excludes SS.
  • A case study presented a 62-year-old woman with a history of SS who developed symptoms that led to both conditions being diagnosed through various tests and biopsies.
  • This case contributes to the understanding of the possible coexistence of sarcoidosis and SS, highlighting the need for awareness in clinical diagnosis.*
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Unlabelled: Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune disease that affects many organs. In this report, we discuss the case of a patient with SLE who presented to an out-hospital clinic, complaining of fever and pain with genital ulcers. Negative evaluations for other causes of genital ulcers, indicated these ulcers as related to SLE.

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Unlabelled: The incidence of neurological injury in primary Sjogren's syndrome varies between 2.5 and 60%. The authors aimed to evaluate its prevalence and characteristics in patients with primary Sjogren's syndrome in a sample of the Syrian population.

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Unlabelled: The association between adult-onset Still's disease (AOSD) and malignancy has previously been observed. However, only a limited number of cases described a combination of AOSD and leukemia, none of which reported AOSD-related symptoms as the first manifestation of acute myeloid leukemia (AML). This presentation might represent a paraneoplastic syndrome or leukemic arthritis mimicking AOSD.

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