Publications by authors named "Tasmin Nazim"
() drug resistance is a major challenge in eradicating its infection globally. is continuously evolving to overcome the anti-TB drug stress and retain its survival inside the host cells. This continuous evolution of can only be tackled by the continuous search for novel drug targets as well as developing new therapeutics.
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- Researchers aimed to find new uses for existing drugs by targeting the RNA methyltransferase Rv3366 (spoU), which is important for RNA modification and is not similar to human proteins.
- The study identified Levodopa and Droxidopa as potential inhibitors of Rv3366 through advanced computational modeling and molecular dynamics simulations, suggesting these drugs for further investigation against drug-resistant TB.