[The comprehensive pathogenetic approach to the neuro-orthopedic rehabilitation of the children of different age presenting with cerebral palsy].

Objectives: The present study was aimed at the improvement of comprehensive neuro-orthopedic rehabilitation of the children of different age presenting with cerebral palsy.

Material And Methods: A total of 267 patients with infantile cerebral paralysis at the age from 1 year to 16 years were available for the observation including 158 (59.2%) boys and 109 (40.

[Regularities of lateral distribution of uranium and thorium decay series radionuclides in the anthropogenically changed soils from the area of radium production waste storage].

Cartographical investigations of the territory of radium production waste storage has shown some changes in lateral differentiation of radionuclides of uranium and thorium decay series to occur during 27 years (1981-2008). Those changes are caused mostly by flat denudation typical for fluvial terrace. At present radionuclides of uranium and thorium decay series are concentrated mostly in flood lands and relief depressions.

[Adaptive reactions of dehydrogenation processes in root voles during additional impacts of the physical nature].

Variations of the dehydrogenation enzyme activity (succinate dehydrogenase, pyruvate dehydrogenase, lactate dehydrogenase) in the heart muscle, liver and brain of root voles (Microtus oeconomus Pall.) and their progeny associated with additional stress effects (chronic low-level gamma-irradiation, short-term exposure to cold) have been studied. Root voles (parents) were caught in the areas with a normal and high-level natural radioactivity in the Republic of Komi.

[Participation of the lipid peroxidation processes in the adaptation mechanism of Muridae like rodents to the radioactive contamination of the Chernobyl NPP zone].

Results of the comparative analysis of the complex investigation of rodent population state caught at areas with different levels of contamination in the accident zone of the Chernobyl NPP during 1986-1993 and 2007, at areas with a practically normal radiation background in the neighborhood of the Kiev City in 1993 and at areas with the normal and increased radiation background in Ukhta region of Komi Republic in 1993-2008 are presented. It is shown that the absence of the linear dependence in changes of the lipid peroxidation (LPO) regulatory system parameters in rodent tissues on the dose of the external gamma-radiation at areas of their trap persists for a long time. Different ability to normalization of the studied indices and nonlinearity of their dose dependences allow us to suggest that changes of the scale and direction of interrelations between the reciprocal parameters of the LPO regulatory system in norm in tissues of rodents which were caught in the accident zone and at areas with an increased radiation background should be the information signal determining selection of the strategy of adaptation to the chronic radiation factor action.

[Ecological and genetic monitoring of muridae from populations undergone to the chronic irradiation].

In work the data of long-term researches of consequences of chronic irradiation and radioactive pollution on a population of muridaea living in a zone of failure on the Chernobyl atomic power station and in territory of Northern radioecological station are resulted. It is shown, that chronic influence by investigated factors leads to authentically significant change of size of the genetic load determined on a level cytogenetic damages, intensity of reproduction, fertility.

[Characteristics of morphogenesis and growth processes of conifers in the Chernobyl nuclear accident zone].

In the article we present data on the study of morphogenesis and of growth processes of Scotch pine (Pinus sylvestris L.) and of Norwey spruce (Picea abies (L.) Karst.

[The effects on non-human species inhabiting areas with enhanced level of natural radioactivity in the north of Russia].

The results of long-term radioecological investigations in areas with enhanced level of natural radioactivity in the north of Russia were summarized. Negative changes in animals and in plants inhabiting areas with increased level of natural radioactivity in Komi Republic were revealed. These changes were reveased in increased levels of chromosomal and genomic mutations, destructive processes in internal tissues of animals, disturbances of reproductive functions and reduction of posterity's viability.

Effects on non-human species inhabiting areas with enhanced level of natural radioactivity in the north of Russia: a review.

Results of long-term radioecological investigations in areas with an enhanced level of natural radioactivity in the north of Russia are summarized. Deleterious changes within animal and plant populations inhabiting areas with an enhanced level of natural radioactivity in the Komi Republic were revealed. These changes are expressed in enhanced levels of mutagenesis, destructive processes in the tissues of animals, disturbances of reproductive functions and reduced offspring viability.

[Genetic aspects of the irradiation in small doses of laboratory lines and experimental populations Drosophila melanogaster].

One of explanations of revealed effects of small doses of an irradiation is induced genetic instability on which background there is a realization of the various radiobiological reactions resulting as to stimulation, and significant oppression of the vital functions of a cell or an organism. In work the given estimations of consequences of an irradiation in small doses of mutant lines of the drosophila are submitted. Paramount value in definition of their size and an orientation of reaction of a genotype is supposed, that, have processes leaders to change of activity of mobile genetic elements and programmed destruction of a cell.

[The genetic effects induced by an irradiation in low doses at Drosophila melanogaster].

This article generalizes the results received by authors in researches of genetic effects of an irradiation for Drosophila. It is supposed, that the main effect of low intensity irradiation is connected with the induced genetic instability on which background the realization of effects of a different direction is possible.

[The regulation of the oxidative processes in the tissues of Muridae like rodents caught in the Chernobyl accident zone].

The results of the investigations of the radioactive contamination consequences on the lipid peroxidation (LPO) processes in organs and tissues of wild rodents which were caught in the Chernobyl NPP accident 30-km zone during 1986-1993 are generalized. The behaviors of the technogenic contamination effect on dynamic of changes of the LPO physico-chemical regulatory system parameters and the generalized parameters of the phospholipid composition in organs of the different radioresistance wild rodents are revealed in dependence on the radioactive contamination level and the duration of the radiation factor exposure. Different sensitivity of the LPO regulatory system parameters in wild rodent tissues to the radioactive contamination of their environment and the unequal ability to normalization of the antioxidant status and the energy exchange in tissues result in the change of the scale and character of interrelations between the reciprocal parameters in norm and have an influence on the development of qualitatively new subpopulations of wild rodents due to the transition of the cell regulatory system to the another level of the function.

[The ecology-genetic consequences of chronic irradiation for the populations of the plants and animals].

The modem presentations are considered in the review about the consequences for the genotype of animals and of plants of the chronic action of factors of low intensity. Inoffer is spoken about possible dug the chronic irradiation in small doses in microevolution events.

[Genotoxicity and toxicity assay of water sampled from the underground nuclear explosion site in the north of the Perm region (Russia)].

The results of our study revealed a local biologically relevant surface water contamination in the radionuclide anomaly in the north of Russia (Perm region) by means of Allium shoenoprasum L. the anaphase-telophase chromosome aberration assay. This radionuclide anomaly was formed in 1971 as a result of an underground nuclear explosion with soil excavation.

Genotoxicity and cytotoxicity assay of water sampled from the underground nuclear explosion site in the north of the Perm region (Russia).

The results of our study revealed a local biologically relevant surface water contamination in the radionuclide anomaly in the north of Russia (Perm region) by means of Allium schoenoprasum L. anaphase-telophase chromosome aberration assay. This radionuclide anomaly was formed in 1971 as a result of an underground nuclear explosion with soil excavation.

[Results of the studies on radiation ecology and radiation biology at the Institute of Biology of Komi Science Center of Ural division of Russian Academy of Science (on 40th anniversary of the Department of Radiation Ecology)].

Information about the foundation and history of the Radiation Ecology Department and results of the researches on the effect of increased background radiation level on plant and animal populations, migration of radionuclides in natural biocoenosies with increased radiation level are presented.

[Current aspects of radiobiology of Drosophila melanogaster. Apoptosis and aging].

The mechanisms of post radiation life span alteration are reviewed and discussed. The mechanisms underlying radiation induced organism aging and death are not well understood and under great interest. What is the cause of radiation-induced "aging"? What are the mechanisms leading to senescence and death? Recent achievements in molecular biology and genetics suggest that cell senescence is determined by telomeres reduction (Biokhimiya, 1997).

[Influence of radioactive pollution on the character of the distribution of wild mouselike rodents according to the measure of lipid antioxidant activity in their organs].

The estimation of the degree of the radioactive contamination effect on the antioxidative status in tissues of rodents from natural populations is done by means of biometric methods. It is shown, that the character of distribution and variability of the lipids antioxidant activity (AOA) differs significantly depending of species and age of animals, the degree of contamination on areas where wild rodents were caught and time during which the radioactive factor affected. The change in character of the animals distribution in AOA of the brain lipids for the more radioresistant Clethrionomys glareolus Schreb, occurs the later than for the more radiosensitive Apodemus agrarius and especially for Microtus oeconomus Pall.

[The dynamics of the radiation damage and recovery processes in coniferous stands in a 10-kilometer control zone of the accident at the Chernobyl Atomic Electric Power Station].

Properties of morphogenesis, growth dynamics, anatomy and ultrastructure of wood and needle, reproductive processes in coniferous plants were studied under different level of radiation effect in the 10-km zone in 1986-1992. It was established that the full drying of pine forests began under absorbed dose 80-100 Gy/year. Threshold doses, after which repair processes were possible, reached to 10-12 Gy/year for Picea abies and 50 Gy/year for Pinus sylvestris.

[An ecological and geographical test of the seed offspring of Viola matutina Klok. from a 30-kilometer area of the accident at the Chernobyl Atomic Electric Power Station].

The generation of seeds of two populations of Viola matutina Klok. sampled from plants growing within the thirty-kilometers zone of the Chernobyl accident (the reproduction of seeds in 1988) was investigated in the north nursery in Syktyvkar. The decrease of sterile pollen and embryonic lethality among the plants from the strongly contaminated site (exposure rate (1075-1434) pC/(kg.

[The dynamics of the frequency of cytogenetic disorders in micropopulations of murine rodents inhabiting the region of the accident at the Chernobyl Atomic Electric Power Station].

Cytogenetic examination of some species of Muridae from Chernobyl region was carried out in 1986-1993. It was revealed that the dynamic of cytogenetic aberrations in cells of animals from territories with distinct level of radioactive contamination differed.

[A rise in the incidence of teratological changes in Plantago lanceolata L. seedlings of the 5th post-accident reproduction in the 30-kilometer area of the Chernobyl Atomic Electric Power Station].

It was for the first time that of the fifth year of monitoring of Plantago lanceolata L., reproduced within the thirty-kilometer zone of Chernobyl NPP disaster, the authors discovered high incidence of seedlings with various morphological abnormalities. It is suggested that the damages observed are related to the cumulative effect of radiation.

The monitoring of herbaceous seeds in the 30-km zone of the Chernobyl nuclear accident.

Species of wild herbaceous plants growing over a period of 3 years under chronic irradiation resulting from the Chernobyl accident were studied. Examining the mass of 1000 seeds and their germination did not yield any significant differences between groups of seeds of the same species collected from different contaminated zones. Nor did the frequency of aberrant cells in roots of germinated seeds reveal any significant differences between zones.

[The structural-functional disorders in the liver of wild rodents from areas of the accident at the Chernobyl Atomic Electric Power Station].

A study was made of the morphological status of hepatocytes, the antioxidant activity of lipids and composition of phospholipids, and dehydrogenase activity in the liver of field mice taken from seven regions of the Chernobyl A.P.S.

[The demonstration of environmental radioactive contamination by its gametocidal action].

Two Viola matutina Klok. populations growing in two areas of the thirty-kilometer zone of Chernobyl varying in gamma radiation background have been studied. Stable, repeated (during a period of 1987-1988) differences between the populations with respect to the amount of sterile pollen and the pattern of anther distribution curves have been revealed.

[Seed regeneration in a natural population of Plantago lanceolata L. in areas with different gamma background levels].

On the basis of the individual analysis of Plantago lanceolata L. nonhomogeneity of its natural population within the thirty-kilometer zone of Chernobyl (reproduction of 1989) has been revealed. It is displayed by lower levels of seed productivity of plants growing in the areas with a high level of radioactive contamination.