3,5,6-Tri-chloro-pyridin-2-ol.

The title compound, CHClNO, is almost planar. In the crystal, the mol-ecules form centrosymmetric hydrogen-bonded dimers through pairwise O-H⋯N inter-actions to generate (8) loops.

VTA Excitatory Neurons Control Reward-driven Behavior by Modulating Infralimbic Cortical Firing.

The functional dichotomy of anatomical regions of the medial prefrontal cortex (mPFC) has been tested with greater certainty in punishment-driven tasks, and less so in reward-oriented paradigms. In the infralimbic cortex (IL), known for behavioral suppression (STOP), tasks linked with reward or punishment are encoded through firing rate decrease or increase, respectively. Although the ventral tegmental area (VTA) is the brain region governing reward/aversion learning, the link between its excitatory neuron population and IL encoding of reward-linked behavioral expression is unclear.