Ethnic differences in glycated haemoglobin between white subjects and those of South Asian origin with normal glucose tolerance.

Objective: To determine whether ethnic differences exist in glycated haemoglobin between white subjects and those of South Asian origin with normal glucose tolerance (NGT) METHODS: Erythrocyte glycated haemoglobin (HbA(1c)) was compared between white subjects and those of South Asian origin with NGT defined by a 75 g oral glucose tolerance test (OGTT).

Results: 139 subjects with NGT comprising 36 people of South Asian origin (20 female) and 103 white subjects (49 female) were compared. Subjects of South Asian origin were younger (p<0.

Does HbA1C predict isolated impaired fasting glycaemia in the oral glucose tolerance test in subjects with impaired fasting glycaemia?

Background: To assess the usefulness of erythrocyte glycated haemoglobin (HbA1C) as a screening tool to identify those subjects with impaired fasting glycaemia (IFG) who do not have impaired glucose tolerance (IGT) or diabetes mellitus (DM) on a 75 g oral glucose tolerance test (OGTT). Design and methods All subjects undergoing an OGTT had HbA1C measured at baseline. Receiver operator characteristics analysis was used to identify optimal HbA1C cut-off values for diagnosing and excluding IGT and DM.

Screening for Addison's disease in patients with type 1 diabetes mellitus and recurrent hypoglycaemia.

Background: Addison's disease may present with recurrent hypoglycaemia in subjects with type 1 diabetes mellitus. There are no data, however, on the prevalence of Addison's disease presenting with recurrent hypoglycaemia in patients with diabetes mellitus.

Methods: Three year retrospective study of diabetic patients with "unexplained" recurrent hypoglycaemia investigated with a short Synacthen test to exclude adrenocortical insufficiency.