Adrenomedullin and Its Possible Role in Improved Survival in Female Patients with Sepsis: A Study in the South East Asian Region.

Aims And Objectives: Serum adrenomedullin (ADM) as a prognostic biomarker to study the gender-related differences in mortality pattern and its correlation with the sequential organ failure assessment (SOFA) and acute physiologic assessment and chronic health evaluation II (APACHE II) scores in patients of sepsis.

Measurements And Main Results: Eighty patients of sepsis of which 36 were males and 44 were females, were taken in the study as per sepsis III guidelines. They were followed up for a period of 28 days.

Hormonal profile in children with isolated hypospadias associates better with comprehensive score of local anatomical factors as compared to meatal location or degree of chordee.

Background: To evaluate if hormonal profile of children with isolated hypospadias (IH) associates better with comprehensive local anatomical factor score (LAFS) than with clinically adjudged urethral meatus location or severity of chordee/k.j.

Material And Methods: Ninety-nine children with IH were enrolled, as per inclusion criteria.

Interaction of low-frequency axisymmetric ultrasonic guided waves with bends in pipes of arbitrary bend angle and general bend radius.

The use of ultrasonic guided waves for the inspection of pipes with elbow and U-type bends has received much attention in recent years, but studies for more general bend angles which may also occur commonly, for example in cross-country pipes, are limited. Here, we address this topic considering a general bend angle φ, a more general mean bend radius R in terms of the wavelength of the mode studied and pipe thickness b. We use 3D Finite Element (FE) simulation to understand the propagation of fundamental axisymmetric L(0,2) mode across bends of different angles φ.

Children with isolated hypospadias have different hormonal profile compared to those with associated anomalies.

Aim: The objective of this study is to compare the hormonal profile of children with isolated hypospadias to controls and hypospadiacs with associated anomalies.

Study Design: Prospective observation at a tertiary referral hospital.

Study Subjects: One hundred consecutive children (0-12 years) with isolated hypospadias (H), 23 with hypospadias and associated anomalies (HO).

Breast cancer: interaction between oxidant-antioxidant dynamics and inflammation in Indian females.

Objectives: Oxidative stress and pro-inflammatory mediators have been implicated in breast carcinogenesis. We attempted to evaluate the markers of oxidative stress, antioxidant mechanism and the inflammatory pathway in patients with breast cancer.

Methods: This study was carried out in departments of Biochemistry and Surgery, Maulana Azad Medical College and associated Hospitals, New Delhi, India.

Pyrazinamide blood concentrations in children suffering from tuberculosis: a comparative study at two doses.

What Is Already Known About This Subject: Pyrazinamide is recommended in doses varying from 15 to 40 mg kg(-1). The most commonly used average daily dose is 25 mg kg(-1). Its use is associated with dose dependent hepatotoxicity.