Publications by authors named "Tarisai Marere"
Antenatal hepatitis B virus sero-prevalence, risk factors, pregnancy outcomes and vertical transmission rate within 24 months after birth in a high HIV prevalence setting.
Kerina Duri Privilege Tendai Munjoma Hope Mataramvura Arthur John Mazhandu Panashe Chandiwana Tarisai Marere
BMC Infect Dis
October 2023
Background: Despite the availability of an effective vaccine, chronic hepatitis B virus (HBV) infections remain a major cause of liver cirrhosis and hepatocellular carcinoma. HBV burden in pregnancy, risk factors and the timing of mother to child transmission remain poorly described especially during this era of lifelong use of Tenofovir/Lamivudine/Efavirenz as firstline for HIV treatment. We aimed to determine the burden of HBV in pregnancy and infants receiving their first dose of HBV vaccine 6 weeks after birth in a high HIV-prevalence setting.
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- The study investigates the vaginal microbiota and immune factors in pregnant African women, comparing those who are HIV-infected to those who are HIV-uninfected, highlighting significant differences in microbiota diversity and structure between the two groups.
- Results indicate that HIV infection is linked to a more diverse vaginal microbiota and an increased risk of preterm birth, with HIV-infected women experiencing a 31% risk of preterm birth compared to 15.3% for HIV-uninfected women.
- The researchers suggest that more longitudinal studies with precise gestational age tracking are necessary to further explore these findings and their implications for maternal and neonatal health.