Background: Sutural anatomy variation has long been a topic of debate among anatomists, paleontologists, and morphologists. While the exact reasons for the prevalence of this variance remains a topic of ongoing discussion, developmental and genetic factors are hypothesized to be the main reasons. Understanding the morphology and occurrence of normal sutural variations in pediatric patients is essential to making the right diagnosis, where a misinterpretation of a sutural bone may lead to an inaccurate assessment, completely misleading the diagnostic process.
View Article and Find Full Text PDFThe term Moyamoya , or "puff of smoke" in Japanese , was first used in 1969 by Suzuki and Takaku to describe the classical appearance of collateral blood vessels in response to progressive vascular stenosis of distal internal carotid artery (ICA). Such condition may result in various clinical presentations ranging from strokes to developmental delays. In order to cease the progression of such stenotic vasculopathy, several means of revascularization have been developed over the years.
View Article and Find Full Text PDFBackground: Gorlin-Goltz syndrome is a rare autosomal dominant disorder resulting from PTCH1 gene mutation and presents with variable clinical manifestations. The co-occurrence of medulloblastoma and cardiac fibroma in Gorlin-Goltz syndrome is extremely rare. The present article discusses a patient diagnosed with Gorlin-Goltz syndrome and concurrent medulloblastoma and cardiac fibroma.
View Article and Find Full Text PDFObjectives: To determine the prevalence of shunt malfunction without change in ventricle size in imaging modalities, and its clinical presentation.
Methods: A cross-sectional study conducted at King Abdulaziz Medical City, Riyadh, from June 2015 to May 2019. Patient's demographics, clinical presentation and changes in ventricle size were collected.
In the original article, the author names were published incorrectly. The names are correct in this publication.
View Article and Find Full Text PDFPurpose: Children with unresectable brainstem-infiltrated ganglioglioma have poor progression-free survival when treated with conventional chemotherapy and radiation regimens. The BRAF mutation occurs in a large number of gangliogliomas, making them amenable for targeted therapy using mutation-specific kinase inhibitors. However, limited data exists on the effectiveness and best treatment duration of these inhibitors in this tumor setting.
View Article and Find Full Text PDFWe present a case of a preterm boy (born at 35 weeks of pregnancy) who was delivered urgently by a caesarean section due to placental abruption. The baby was found to have a tense fontanelle leading to imaging that showed a 5.5 cm right intraventricular mass centred in the atrium, hydrocephalus and extensive surrounding vasogenic oedema.
View Article and Find Full Text PDF