Publications by authors named "Tarin P Barrera-Lechuga"
Article Synopsis
- Metabolic syndrome (MetS) is a global health issue linked to cardiovascular problems, particularly affecting heart function through abnormalities in the cardiac excitation-contraction coupling (ECC) mechanism.
- Research on rats revealed that MetS altered Ca handling in cardiomyocytes, resulting in decreased Ca transient amplitude and contractility, along with reduced Ca spark activity.
- Key findings indicate that diminished phosphorylation of the ryanodine receptor (RyR2) and reduced SERCA pump activity contribute to Ca mishandling in MetS hearts, potentially impairing heart function.
