Publications by authors named "Tarik Avdic"

Article Synopsis
  • The study investigates long-term trends and risk factors for peripheral arterial complications in individuals with type 2 diabetes compared to the general population, using data from the Swedish National Diabetes Register from 2001 to 2019.
  • It includes a large sample size of 655,250 people with diabetes, analyzing the incidence rates of various complications over the years, such as lower extremity artery disease and diabetic foot disease.
  • Key findings reveal that risk factors like hemoglobin A1c levels, systolic blood pressure, smoking, and lipid levels significantly influence these complications, with higher risk for those not meeting target levels.
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Article Synopsis
  • This study analyzed long-term trends and risk factors for non-coronary complications in individuals with type 1 diabetes compared to matched controls using a large dataset from the Swedish National Diabetes Register.
  • Between 2001 and 2019, the incidence rates of complications like large artery disease and diabetic foot syndrome decreased significantly in those with type 1 diabetes, while certain risk factors like education and blood sugar levels had a substantial impact on these outcomes.
  • Interestingly, people with type 1 diabetes who maintained cardiometabolic risk factors at target levels showed lower risks for some complications, but had a significantly higher risk for diabetic foot disease if all risk factors were present.
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Article Synopsis
  • Type 2 diabetes (T2D) and peripheral artery disease (PAD) are linked to higher mortality rates, with this study examining the mortality risks of those with T2D after developing PAD compared to individuals without T2D.
  • The research included over 150,000 individuals with T2D and 346,000 matched controls, utilizing national registries to analyze risk factors, comorbidities, and outcomes through statistical models.
  • Results indicated that people with T2D experienced higher rates of all-cause and cardiovascular mortality following PAD onset, with adjusted hazard ratios showing a significant increase in mortality risk for those with T2D.
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Objective: To investigate to what extent having control of peripheral artery disease (PAD) risk factors is associated with the risk of incident PAD in individuals with type 2 diabetes.

Research Design And Methods: A total of 148,096 individuals with type 2 diabetes in the Swedish National Diabetes Register between 2005 and 2009 were included and matched with 320,066 control subjects on the basis of age, sex, and county. A few control subjects who developed type 2 diabetes after recruitment, during wash-in (<0.

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Epidemiological data indicate decreased risk for development and growth of abdominal aortic aneurysm (AAA) among patients with diabetes mellitus (DM). On the other hand, DM adds to increased cardiovascular (CV) morbidity and mortality. In a nationwide observational cohort study of patients registered in the Swedish Vascular Register and the Swedish National Diabetes Register, we evaluated potential effects of DM on total mortality, CV morbidity, and the need for reintervention after elective endovascular aneurysm repair (EVAR) for AAA.

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Background: No studies have examined long-term risks for aortic aneurysm (AA) and aortic dissection (AD) or mortality after AA or AD hospitalization among patients with type 2 diabetes mellitus (T2DM).

Methods And Results: In this observational cohort study, we linked data for patients with T2DM in the Swedish National Diabetes Register, and 5 individually matched population-based control subjects (CSs) without diabetes mellitus (on the basis of sex, age, and county), to other national databases to capture hospitalizations and death. We examined the risk of hospitalization for AA and AD, as well as mortality risk after AA and AD using Kaplan-Meier curves and Cox regression hazards models.

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Background: Real-world data regarding indications for use of insulin pump remain sparse. We investigated characteristics among individuals with type 1 diabetes (T1D) in relation to indication for use of insulin pump (CSII). Comparison was made with T1D subjects using multiple daily injections (MDI).

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Objective: To investigate the long term effects of continuous subcutaneous insulin infusion (insulin pump therapy) on cardiovascular diseases and mortality in people with type 1 diabetes.

Design: Observational study.

Setting: Swedish National Diabetes Register, Sweden 2005-12.

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