Stool antigen detection versus C-urea breath test for non-invasive diagnosis of pediatric infection in a limited resource setting.

Introduction: The prevalence of childhood infection with is high, especially in developing countries. Non-invasive methods for detection of infection in children should be inexpensive, easy to perform, well tolerated and have a high diagnostic accuracy. We aimed to compare the reliability, specificity and sensitivity of the stool antigen (HpSA) test with the C-urea breath test (C-UBT) for the diagnosis of infection in a limited resource setting.

Association of macrophage migration inhibitory factor promoter polymorphism -173G/C with susceptibility to childhood asthma.

Introduction: Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine that plays an important role in the pathogenesis of asthma. Polymorphisms associated with inflammatory diseases exist in the promoter region of MIF, which alter its expression. We aimed to study the association of MIF promoter polymorphism -173G/C with childhood asthma.

The burden of different pathogens in acute diarrhoeal episodes among a cohort of Egyptian children less than five years old.

Introduction: Diarrhoea continues to cause significant morbidity in Egypt.

Aim: To determine the frequency and distribution of different enteropathogens in acute diarrhoeal episodes, utilising an expanded testing regimen, and to correlate clinical signs and symptoms associated with the detected pathogens.

Material And Methods: The case-control study enrolled 356 patients < 5 years old with acute diarrhoea and 356 age and sex-matched healthy controls.