A Comprehensive Analysis of 3 Moroccan Genomes Revealed Contributions From Both African and European Ancestries.

Genetic variations in the human genome represent the differences in DNA sequence within individuals. This highlights the important role of whole human genome sequencing which has become the keystone for precision medicine and disease prediction. Morocco is an important hub for studying human population migration and mixing history.

Draft Genome Sequences of Two Enterobacter hormaechei subsp. Strains Isolated from the Moroccan Sahara.

We report the draft genome sequences of Enterobacter hormaechei subsp. strains MDMC82 and MDMC76, which were isolated from the sand dunes of the Merzouga desert in the Moroccan Sahara. These bacteria are able to tolerate the harsh environmental conditions of the Moroccan desert.

Draft Genome Sequences of Three Pseudomonas chengduensis Strains Isolated from Desert Soil in Morocco.

We report the draft genome sequences of three Pseudomonas chengduensis strains isolated from the sand dunes of the Merzouga (MDMC17 strain) and Erg Lihoudi (MDMC216 and MDMC224 strains) regions in the Moroccan desert. These bacteria are able to tolerate the harsh environmental conditions of the desert ecosystem.

Infection Strategy in Wheat Involves a Highly Conserved Genetic Program That Controls the Expression of a Core Effectome.

, the main causal agent of Fusarium Head Blight (FHB), is one of the most damaging pathogens in wheat. Because of the complex organization of wheat resistance to FHB, this pathosystem represents a relevant model to elucidate the molecular mechanisms underlying plant susceptibility and to identify their main drivers, the pathogen's effectors. Although the catalog of effectors has been well characterized at the genome scale, in planta studies are needed to confirm their effective accumulation in host tissues and to identify their role during the infection process.

Comparative Genomics of Eight Strains with Contrasting Aggressiveness Reveals an Expanded Open Pangenome and Extended Effector Content Signatures.

, the primary cause of Fusarium head blight (FHB) in small-grain cereals, demonstrates remarkably variable levels of aggressiveness in its host, producing different infection dynamics and contrasted symptom severity. While the secreted proteins, including effectors, are thought to be one of the essential components of aggressiveness, our knowledge of the intra-species genomic diversity of is still limited. In this work, we sequenced eight European strains of contrasting aggressiveness to characterize their respective genome structure, their gene content and to delineate their specificities.

Large scale genomic analysis of 3067 SARS-CoV-2 genomes reveals a clonal geo-distribution and a rich genetic variations of hotspots mutations.

In late December 2019, an emerging viral infection COVID-19 was identified in Wuhan, China, and became a global pandemic. Characterization of the genetic variants of SARS-CoV-2 is crucial in following and evaluating it spread across countries. In this study, we collected and analyzed 3,067 SARS-CoV-2 genomes isolated from 55 countries during the first three months after the onset of this virus.

Searching for FHB Resistances in Bread Wheat: Susceptibility at the Crossroad.

Fusarium head blight (FHB), primarily caused by , is one of the most devastating fungal wheat diseases. During the past decades, many efforts have been deployed to dissect FHB resistance, investigating both the wheat responses to infection and, more recently, the fungal determinants of pathogenicity. Although no total resistance has been identified so far, they demonstrated that some plant functions and the expression of specific genes are needed to promote FHB.

Clonal diversity and detection of carbapenem resistance encoding genes among multidrug-resistant isolates recovered from patients and environment in two intensive care units in a Moroccan hospital.

Background: Carbapenem-resistant has recently been defined by the World Health Organization as a critical pathogen. The aim of this study was to compare clonal diversity and carbapenemase-encoding genes of isolates collected from colonized or infected patients and hospital environment in two intensive care units (ICUs) in Morocco.

Methods: The patient and environmental sampling was carried out in the medical and surgical ICUs of Mohammed V Military teaching hospital from March to August 2015.