Publications by authors named "Taral Patel"
Electrochemical grafting of organic molecules to metal surfaces has been well-known as an efficient tool enabling tailored modification of surface at the nanoscale. Among many compounds with the ability to undergo the process of electrografting, iodonium salts belong to less frequently used, especially when compared with the most popular diazonium salts. Meanwhile, due to their increased stability, iodonium salts may be used in situations where the use of diazonium salts is constrained.
View Article and Find Full Text PDFObjectives: There is limited data on race and outcomes of chronic total occlusion (CTO) percutaneous coronary intervention (PCI). The authors sought to evaluate CTO PCI techniques and outcomes in different racial groups.
Methods: We examined the baseline characteristics and procedural outcomes of 11 806 CTO PCIs performed at 44 US and non-US centers between 2012 and March 2023.
Article Synopsis
- Retrograde chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has lower success rates and higher complications compared to the antegrade method, yet its outcomes and techniques were evaluated in this study involving over 4,000 cases.
- The study found that retrograde crossing was successful in about 60.5% of cases, with technical success rates of 78.7% and a 3.5% rate of major adverse cardiac events (MACE) during hospitalization.
- Among various retrograde techniques, retrograde true lumen puncture showed the best safety profile, but overall there is room for improvement in both the efficacy and safety of retrograde CTO PCI procedures.*
Background: There is limited information on the impact of the target vessel on the procedural techniques and outcomes of chronic total occlusion (CTO) percutaneous coronary intervention (PCI).
Methods: We analyzed the baseline clinical and angiographic characteristics and procedural outcomes of 11,580 CTO PCIs performed between 2012 and 2022 at 44 centers.
Results: The most common CTO target vessel was the right coronary artery (RCA) (53.
The design of biomaterials able to facilitate cell adhesion is critical in the field of tissue engineering. Precise control of surface chemistry at the material/tissue interface plays a major role in enhancing the interactions between a biomaterial and living cells. Bio-integration is particularly important in case of various electrotherapies, since a close contact between tissue and electrode's surface facilitates treatment.
View Article and Find Full Text PDFIn this report, we describe a case involving an 80-year-old female who presented to the emergency department with an acute onset of left upper quadrant abdominal pain. The chief complaint misled us down multiple pathways of considering ischemic bowel disease, peptic ulcer disease, and small bowel obstruction. As a result, this led to costly and invasive diagnostic studies.
View Article and Find Full Text PDFBackground: Death is a rare but devastating complication of chronic total occlusion (CTO) percutaneous coronary intervention.
Methods: We examined the clinical characteristics and procedural outcomes of patients who died periprocedurally in the Prospective Global Registry for the Study of CTO Interventions (PROGRESS-CTO).
Results: Of the 12 928 patients who underwent CTO percutaneous coronary intervention between 2012 and 2022, 52 (0.
Article Synopsis
- - The study focuses on how controlling the surface chemistry of biomaterials can enhance cell behavior, especially regarding cell adhesion, which is crucial for tissue engineering and regenerative medicine.
- - Researchers explored modifying platinum electrodes using diazonium salts and poly-L-lysine to increase sites for cell adhesion, and assessed these electrodes for their chemical properties and wettability.
- - Experiments with human neuroblastoma SH-SY5Y cells demonstrated improved cell adhesion on the treated electrodes, suggesting that this modification approach could effectively improve connections between bioelectronic devices and neural cells.
Balloon uncrossable lesions are defined as lesions that cannot be crossed with a balloon after successful guidewire crossing. We analyzed the association between balloon uncrossable lesions and procedural outcomes of 8671 chronic total occlusions (CTOs) percutaneous coronary interventions (PCIs) performed between 2012 and 2022 at 41 centers. The prevalence of balloon uncrossable lesions was 9.
View Article and Find Full Text PDFBackground: Same day discharge (SDD) following chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has received limited study.
Methods: We evaluated the clinical, angiographic, and procedural characteristics of patients discharged the same day versus those kept for overnight observation in the Prospective Global Registry for the Study of Chronic Total Occlusion Intervention (PROGRESS-CTO, NCT02061436).
Results: Of the 7181 patients who underwent CTO PCI, 943 (13%) had SDD.
Introduction: The most common reason for constructing an arteriovenous fistula (AVF) is chronic kidney disease. Various factors are associated with nonmaturation or failure of AVF, which can be evaluated using color Doppler/duplex ultrasound (DUS). We carried out this study to evaluate the role of pre- and postoperative DUS for the prediction of outcomes of wrist radiocephalic (RC) AVF.
View Article and Find Full Text PDFArticle Synopsis
- Bivalirudin is rarely used in chronic total occlusion (CTO) percutaneous coronary interventions (PCI), with only 0.75% of procedures utilizing it in a study from 2012 to 2022.
- There were no significant differences in primary outcomes like net adverse cardiac events (NACE), major adverse cardiac events (MACE), or vascular complications between the bivalirudin and unfractionated heparin groups.
- Further research is necessary to evaluate the safety and efficacy of bivalirudin for CTO-PCIs, given its limited use and comparable outcomes to traditional heparin.
Background: Guidewires and microcatheters are critical to the success of chronic total occlusion (CTO) percutaneous coronary intervention (PCI).
Methods: We examined equipment utilization in 11,202 CTO-PCIs performed in 10,952 patients at 42 United States (US) and non-US centers between 2012 and 2022.
Results: Antegrade-only crossing was attempted in 7628 CTO-PCIs (68%) and the retrograde approach was used in 3574 CTO-PCIs (32%).
In this study, wet catalytic decomposition of Orange (II) dye was carried out with tungsten and iron bimetal-incorporated mesoporous SBA-15 (W-Fe@SBA-15) under visible light. The synthesized hybrid composite material was characterized by physicochemical methods, powder X-ray diffraction (PXRD) spectroscopy, scanning electron microscopy combined with energy-dispersive X-ray (SEM-EDX) spectroscopy studies, Fourier transform infrared (FT-IR) spectroscopy, transmission electron microscopy (TEM), atomic force microscopy (AFM), thermogravimetric analysis (TGA), and surface property studies to understand the nature of the dye degradation process and for catalytic studies. The maximum degradation of Orange (II) dye measured by a UV-visible spectrophotometer was 99% at a contaminant volume of 2.
View Article and Find Full Text PDFWe present a case of a 32-year-old male who developed capecitabine-induced phimosis which resolved spontaneously without the need for circumcision within a few days of discontinuation of chemotherapy. The patient was on capecitabine with irinotecan chemotherapy for peritoneal metastasis from adenocarcinoma of the lower esophagus. A detailed literature review showed a few case reports with penile and scrotal erythema, ulceration, and swelling along with hand-foot syndrome, but none reported the occurrence of phimosis with spontaneous resolution.
View Article and Find Full Text PDFArticle Synopsis
- Approximately 6.3% of patients who underwent chronic total occlusion percutaneous coronary intervention (CTO-PCI) between 2012 and 2022 presented with acute coronary syndrome (ACS).
- ACS patients tended to be older and had a higher prevalence of comorbid conditions, but technical success rates and major adverse cardiovascular events (MACE) were similar to those without ACS.
- The study suggests that performing CTO-PCI on ACS patients yields comparable outcomes to non-ACS patients.
Background: Preprocedural coronary computed tomography angiography (CCTA) can be useful in procedural planning for chronic total occlusion (CTO) percutaneous coronary intervention (PCI).
Methods: We examined the clinical, angiographic and procedural characteristics and outcomes of cases with vs. without preprocedural CCTA in PROGRESS-CTO (NCT02061436).
Article Synopsis
- The study investigates balloon undilatable lesions in chronic total occlusion (CTO) percutaneous coronary intervention (PCI), an area that has not been thoroughly researched.
- About 8.5% of CTO lesions are identified as balloon undilatable, with affected patients being older and having more comorbidities compared to other patients undergoing PCI.
- Treatment for these lesions shows lower technical success rates and a higher risk of major adverse cardiovascular events (MACE) during hospitalization.*
Background: The relationship between left ventricular ejection fraction (LVEF) and the success and safety of coronary chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has received limited study.
Methods: We examined the clinical characteristics and outcomes of CTO PCI in the Prospective Global Registry for the Study of CTO Intervention (PROGRESS-CTO) after stratifying patients by LVEF (≤35%, 36%-49%, and ≥50%).
Results: A total of 7827 CTO PCI procedures with LVEF data were included.
Background: The outcomes of distal radial access (dRA) in chronic total occlusion percutaneous coronary intervention (CTO-PCI) have received limited study.
Methods: We compared the clinical, angiographic, and procedural characteristics of 120 CTO-PCIs performed via dRA access with 2625 CTO-PCIs performed via proximal radial access (pRA) in a large, multicenter registry.
Results: The dRA group had lower mean PROGRESS-CTO score than the pRA group (1.
Impact of adherence to the hybrid algorithm for initial crossing strategy selection in chronic total occlusion percutaneous coronary intervention.
Rev Esp Cardiol (Engl Ed)
December 2021
Introduction And Objectives: The hybrid algorithm was designed to assist with initial and subsequent crossing strategy selection in chronic total occlusion (CTO) percutaneous coronary interventions (PCIs). However, the success of the initially selected strategy has received limited study.
Methods: We examined the impact of adherence to the hybrid algorithm recommendation for initial CTO crossing technique selection in 4178 CTO PCIs from a large multicenter registry.
Background: The impact of intravascular ultrasound (IVUS) utilization for stent optimization on the long-term outcomes in chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has received limited study.
Methods: We examined the outcomes of CTO-PCI with and without IVUS use for stent optimization in 922 CTO-PCIs performed between 2012 and 2019 at 12 United States centers. Major adverse cardiac event (MACE) was defined as the composite of cardiac death, acute coronary syndrome, and target-vessel revascularization.
Background: The impact of chronic total occlusion (CTO) percutaneous coronary intervention (PCI) on angina and subsequent incidence of major adverse cardiovascular event (MACE) rate remains controversial.
Methods: We compared patient- reported angina change and the incidence of MACE (defined as death, myocardial infarction [MI], target-vessel revascularization) between successful vs failed CTO-PCI in 1612 patients participating in a large, multicenter registry.
Results: CTO-PCI was successful in 1387 patients (86%).