Food Addit Contam Part A Chem Anal Control Expo Risk Assess
February 2022
Cattle that were at steady-state serum polyfluoroalkyl substances (PFAS) concentrations due to several years of exposure to water contaminated by residues of Aqueous Film-Forming (AFFF) firefighting foam had perfluorooctane sulphonate (PFOS) isomers, perfluoroheptane sulphonate (PFHpS), perfluorohexane sulphonate (PFHxS), perfluorononanoic acid (PFNA) and perfluorodecanoic acid (PFDA) in serum. Elimination serum half-lives were determined in five heifers from serial blood sampling over 215 days. Eleven additional animals that had blood sampled on day 19 (d19) were euthanised on d63.
View Article and Find Full Text PDFFood Addit Contam Part A Chem Anal Control Expo Risk Assess
November 2021
In this study accumulation has been determined of several per- and polyfluoroalkyl substances (PFAS) from ingested water to steady state serum concentration for adult beef cattle and sheep raised on a hobby farm impacted by PFAS contamination. PFAS concentrations in stock water were stable for more than a year, they were non-measurable in grass but present at very low levels in soil which equated to just 1% of the intake from water. Prior to quantifying PFAS in cattle serum there had been no breeding for 18 months.
View Article and Find Full Text PDFThe lack of Australian species data has pragmatically led to the use of toxicological data from the Northern Hemisphere to develop water-quality guidelines. However, it is unknown whether Australian species and ecosystems are equally as sensitive and if an uncertainty factor is warranted for Australian guideline setting. In the present study, it is hypothesized that an uncertainty factor is not required.
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