The use of arsenic (As) for various industrial and agricultural applications has led to worldwide environmental contamination. Phytoremediation using hyperaccumulators is a sustainable soil As mitigation strategy. Microbial processes play an important role in the tolerance and uptake of trace elements such as in plants.
View Article and Find Full Text PDFWe describe a simple but efficient approach to make fluorescent probes A and B based on rhodol dyes incorporated with salicyaldehyde moiety for monitoring pH changes in mitochondria under oxidative stresses and hypoxia conditions, and for tracking mitophagy processes. Probes A and B possess p values (p ≈ 6.41 and 6.
View Article and Find Full Text PDFThree fluorescent probes , , and that function in the near-infrared wavelengths and utilize pseudo xanthene platforms with an oxygen atom at the 10-position replaced by a [Me-N] group have been created to identify hypoxia via nitroreductase determinations at the 0.04, 0.10, and 0.
View Article and Find Full Text PDFAbnormal levels of glutathione, a cellular antioxidant, can lead to a variety of diseases. We have constructed a near-infrared ratiometric fluorescent probe to detect glutathione concentrations in biological samples. The probe consists of a coumarin donor, which is connected through a disulfide-tethered linker to a rhodamine acceptor.
View Article and Find Full Text PDFRatiometric near-infrared fluorescent probes ( and ) have been prepared for pH determination in mitochondria by attaching dithioacetal and formal residues onto a hemicyanine dye. The reactive formyl group on probe allows for retention inside mitochondria as it can react with a protein primary amine residue to form an imine under slightly basic pH 8.0.
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