Publications by authors named "Tara Holt"
Objective: The objective of this study was to evaluate the effectiveness of 3-factor prothrombin complex concentrate (3F-PCC) compared to 4-factor PCC (4F-PCC) in warfarin-associated bleeding.
Methods: This multicenter, retrospective, cohort study analyzed data from patients admitted between May 2011 and October 2014 who received PCC for warfarin-associated bleeding. The primary outcome was the rate of international normalized ratio (INR) normalization, defined as an INR ≤1.
Major publications in the critical care pharmacotherapy literature in 2015.
Am J Health Syst Pharm
March 2017
Purpose: Recently published practice guidelines and research reports on pharmacotherapy in critical care patient populations are summarized.
Summary: The Critical Care Pharmacotherapy Literature Update (CCPLU) Group is composed of over 50 experienced critical care pharmacists who evaluate 31 peer-reviewed journals monthly to identify literature pertaining to pharmacotherapy in critical care populations. Articles are chosen for summarization in a monthly CCPLU Group publication on the basis of applicability and relevance to clinical practice and strength of study design.
Article Synopsis
- There has been significant growth in the use of anticoagulant therapies, extending from noncritical to critical care settings due to serious complications.
- It’s crucial for critical care practitioners to understand these newer anticoagulant agents to effectively manage patients in the ICU.
- An extensive review is provided to cover the pharmacology, indications, adverse effects, and management strategies related to commonly used anticoagulants.