Adolescent Young Adult Acute Lymphoblastic Leukemia Survivors Develop Innovative Solutions for Unmet Needs.

Adolescent young adult (AYA) cancer survivors continue to have substantive unmet needs. Literature and insights from a task force of survivors, caregivers, and survivor advocates convened by Servier Pharmaceuticals indicate desires for peer created and provided support. This secondary data analysis of information from the task force identified unmet needs in five domains and solutions explored for four prioritized needs.

Using behavioral economics to promote advanced directives for end of life care: a national study on message framing.

Advance directives (AD) are a crucial method for individuals to communicate their directions regarding medical decisions to their families and health care professionals when they are no longer able to make these decisions for themselves. However, not many individuals have an AD. We present the results of a survey-based experiment on how message framing (positive, negative and social norm) in educational videos affects (a) the individual's decision to acquire more information about an AD and (b) the change in stated likelihood of obtaining an AD.

Effective Use of Angiotensin II in Coronavirus Disease 19-Associated Mixed Shock State: A Case Report.

The rapid spread of Coronavirus Disease 2019 (COVID-19) has sparked a search for effective therapies. The discovery that the virus binds the angiotensin-converting enzyme 2 (ACE2) receptor has led to investigation of the renin-angiotensin system for possible therapeutic targets. We present a case of an elderly woman with multiple comorbidities who developed severe acute respiratory distress syndrome (ARDS), a cardiomyopathy, and vasodilatory shock secondary to COVID-19 and was treated with exogenous angiotensin II.

Treatment for Severe Coronavirus Disease 2019 With the Seraph-100 Microbind Affinity Blood Filter.

Unlabelled: To determine whether Seraph-100 (Exthera Medical Corporation, Martinez, CA) treatment provides clinical benefit for severe coronavirus disease 2019 cases that require mechanical ventilation and vasopressor support.

Data Sources: The first two patients in the United States treated with the novel Seraph-100 device. These cases were reviewed by the Food and Drug Administration prior to granting an emergency use authorization for treatment of coronavirus disease 2019.

Contextualizing inclusion: Developing a framework and measure for a military context.

Given recent changes and transitions occurring within the US military, it is imperative - now more than ever - that leaders find a way to leverage demographic and functional diversity in their units to support mission effectiveness. Academic researchers have found that fostering a climate for inclusion, where all individuals feel like they are fairly treated, valued, and included, can maximize the benefits of diversity, while minimizing potential disadvantages. However, no research has systematically explored what it means to assess and develop a climate for inclusion in the military context.

Porches as Enrichment for Singly Housed Cynomolgus Macaques ().

Effective environmental enrichment is used by animals, promotes species-typical behavior, and decreases abnormal behavior. Porches attached to the front of an animal's cage provide additional space, perching opportunities, and a better view of the surroundings. Here we assessed the effectiveness of porches as a form of enrichment and identified characteristics of the animals most likely to use the porches.

Bringing Menu Labelling to Independent Restaurants: Findings from a Voluntary Pilot Project in Toronto.

Toronto Public Health conducted a pilot project to assess the feasibility of menu labelling by independent restaurants. The pilot project was informed by consultations with the industry and other jurisdictions that have implemented a similar initiative. Public Health Dietitians worked closely with these restaurants to help them work toward posting calories and sodium on their menus.

A novel device for accurate and efficient testing for vision-threatening diabetic retinopathy.

Aims: To evaluate the performance of the RETeval device, a handheld instrument using flicker electroretinography (ERG) and pupillography on undilated subjects with diabetes, to detect vision-threatening diabetic retinopathy (VTDR).

Methods: Performance was measured using a cross-sectional, single armed, non-interventional, multi-site study with Early Treatment Diabetic Retinopathy Study 7-standard field, stereo, color fundus photography as the gold standard. The 468 subjects were randomized to a calibration phase (80%), whose ERG and pupillary waveforms were used to formulate an equation correlating with the presence of VTDR, and a validation phase (20%), used to independently validate that equation.

The price they paid.

Background: Several individuals integral to the development of evidence-based medicine endured hardship for their efforts and beliefs.

Case Presentation: We present the history of three individuals who were integral to the formation of evidence-based medicine. All three individuals suffered as a result of resistance to change from colleagues as well as from within the profession.

Immediate changes in temporomandibular joint opening and pain following vibration therapy: a feasibility pilot study.

Objective: The purpose of this pilot study was to determine the scientific and process feasibility in an effort to direct future larger trials.

Methods: Scientific Feasibility: Twelve subjects were randomly allocated to an intervention and a control group. The intervention protocol consisted of intraoral vibration therapy on the muscles of mastication bilaterally for a period of 1 minute per muscle.

Healthy fish consumption and reduced mercury exposure: counseling women in their reproductive years.

Objective: To provide family physicians with a practical, evidence-based approach to counseling women about healthy fish eating.

Sources Of Information: MEDLINE was searched for articles published between 1999 and 2008. Most studies described in this article provide level II or III evidence.

From voice to agency: guiding principles for participatory action research with youth.

This article begins by examining current crises facing historically marginalized youth, which necessitate more critical approaches to youth development and empirical investigations into the challenges that young people face. This requires not only listening to their voices, but actively engaging them in investigations of and interventions into social problems that affect their lives. Researching with youth raises particular dilemmas, however.

Comparison of Wooden and Polyethylene Cutting Boards: Potential for the Attachment and Removal of Bacteria from Ground Beef .

The potentials for removal of beef bacterial microflora from unscored polyethylene and hardwood cutting boards were compared. Ground beef was placed for 0 to 90 min onto cutting boards at room temperature and then removed; the surfaces were swabbed and the bacteria were enumerated. The boards were cleaned with various cleaning agents and then analyzed for bacterial removal.