Triterpenoid Saponins from Maesa argentea Leaves.

Within an ongoing research program on saponins with potential antileishmanial activity, four previously undescribed saponins were isolated from leaves and identified by LC-MS/MS, GC-MS, and 1D and 2D NMR spectroscopy as 3--{([-D-glucopyranosyl-(1 → 2)--L-rhamnopyranosyl-(1 → 2)--D-galactopyranosyl-(1 → 3)]-[-D-galactopyranosyl-(1 → 2)]--D-glucuronopyranosyl)}-21-angeloyloxy-22-butanoyloxy-13,28-oxidoolean-16,28-diol (), 3--{([-D-glucopyranosyl-(1 → 2)--L-rhamnopyranosyl-(1 → 2)--D-galactopyranosyl-(1 → 3)]-[-D-galactopyranosyl-(1 → 2)]--D-glucuronopyranosyl)}-21,22-angeloyloxy-13,28-oxidoolean-16,28-diol (), 3--{([-D-glucopyranosyl-(1 → 2)--L-rhamnopyranosyl-(1 → 2)--D-galactopyranosyl-(1 → 3)]-[-D-galactopyranosyl-(1 → 2)]--D-glucuronopyranosyl)}-21-angeloyloxy-22-()-cinnamoyloxy-13,28-oxidoolean-16,28-diol (), and 3--{([-L-rhamnopyranosyl-(1 → 2)--D-galactopyranosyl-(1 → 3)]-[-D-galactopyranosyl-(1 → 2)]--D-glucuronopyranosyl)}-21-angeloyloxy-22-()-cinnamoyloxy-13,28-oxidoolean-16,28-diol (). Leaf material was obtained from a germinated seed that was clonally propagated using tissue culturing. Compounds - showed structural similarity with maesasaponins and maesabalides reported before from other spp.