Modeling and Optimization of Fractal Dimension in Wire Electrical Discharge Machining of EN 31 Steel Using the ANN-GA Approach.

To achieve enhanced surface characteristics in wire electrical discharge machining (WEDM), the present work reports the use of an artificial neural network (ANN) combined with a genetic algorithm (GA) for the correlation and optimization of WEDM process parameters. The parameters considered are the discharge current, voltage, pulse-on time, and pulse-off time, while the response is fractal dimension. The usefulness of fractal dimension to characterize a machined surface lies in the fact that it is independent of the resolution of the instrument or length scales.

Nano-encapsulation of Dietary Phytoconstituent Capsaicin on Emulsome: Evaluation of Anticancer Activity Through the Measurement of Liver Oxidative Stress in Rats.

Background: Excessive reactive species derived from oxygen and nitrogen leads to oxidative damage to tissue and organs. Capsaicin (CAP), a pungent component found in red pepper can prevent oxidative stress.

Objective: The aim of the present work was to evaluate the protective effects of CAP loaded nano-emulsomes (EML) against the oxidative stress of rat livers induced through sodium fluoride (NaF).

Nano-encapsulation of capsaicin on lipid vesicle and evaluation of their hepatocellular protective effect.

The intention of the study was to evaluate the effectiveness of nanocapsulated food constituent capsaicin in protection of liver oxidative stress. We had prepared phospholipid vesicle (nanoliposome) by formation of thin lipid film followed by hydration when the mean vesicle diameter was found to be 277.7nm.

Self-Powered Broadband Photodetector using Plasmonic Titanium Nitride.

We report the demonstration of plasmonic titanium nitride (TiN) for fabrication of an efficient hybrid photodetector. A novel synthesis method based on plasma nanotechnology is utilized for producing air stable plasma polymerized aniline-TiN (PPA-TiN) nanocomposite and its integration in photodetector geometry. The device performs as a self-powered detector that responds to ultraviolet and visible light at zero bias.

Plasmonic Hot Hole Generation by Interband Transition in Gold-Polyaniline.

Studies on hot carrier science and technology associated with various types of nanostructures are dominating today's nanotechnology research. Here we report a novel synthesis of polyaniline-gold (PAni-Au) nanocomposite thin films with gold nanostructures (AuNs) of desired shape and size uniformly incorporated in the polymer matrix. According to shape as well as size variation of AuNs, two tunable plasmonic UV-Visible absorption bands are observed in each of the nanocomposites.

Infringement of the barriers of cancer via dietary phytoconstituents capsaicin through novel drug delivery system.

Cancer is the major cause of fatality and the number of new cases is increasing incessantly. Conventional therapies and existing anticancer agents cause serious side effects and expand the patient's lifespan by a few years. There is the need to exploit alternative anticancer agents and novel drug delivery system to deliver these agents to the tumor site for the prevention of cancer.

Plasmonic photosensitization of polyaniline prepared by a novel process for high-performance flexible photodetector.

We report the synthesis of a polyaniline (PAni)-gold nanoparticle (AuNP) composite thin film in a single step. A flexible high-performance visible photodetector is constructed using PAni-AuNP composite with low loading of AuNP, and optoelectronic properties of the device are evaluated. The present study demonstrates that a plasmonic hybrid nanocomposite prepared by a single-step novel plasma-based dry process could solve the low lifetime and performance-related issues of organic optoelectronic devices.

Immobilization of trypsin on plasma prepared Ag/PPAni nanocomposite film for efficient digestion of protein.

This work demonstrates the efficacy of a support matrix prepared by plasma process for trypsin immobilization without any surface activator. Plasma polymerization cum sputtering process is used to prepare the nanocomposite support matrix. Plasma sputtered silver nanoparticles (AgNPs) are uniformly embedded into plasma polymerized aniline (PPAni) film.

Highly effective antibiofilm coating of silver-polymer nanocomposite on polymeric medical devices deposited by one step plasma process.

Foley's catheters were coated with Silver (Ag), plasma polymerized aniline (PPAni) and Ag-PPAni composite by plasma based deposition processes which were characterized by XRD, EDX, SEM, and FT-IR spectroscopy and bioassays were performed to validate their efficacies to kill planktonic cells as well as to remove biofilm. The analyses confirmed the formation of Ag nanoparticles (AgNPs), PPAni and Ag-PPAni composite and also corroborated their successful deposition over the catheters. Antibacterial assays showed that coated catheters were capable of killing planktonic cells of most commonly encountered uropathogens and equally capable of eradicating biofilm formation by the uropathogens as evident from the reduced cfu/ml.