Publications by authors named "Taozhi He"
Despite existing evidence linking dyskinesia to levodopa, the primary treatment for Parkinson's, the dose-response relationship and risk factors remain uncertain. In this study, the risk for dyskinesia in patients with Parkinson's disease receiving levodopa was evaluated via meta-analysis and meta-regression approaches to examine dyskinesia risk factors more reliably and improve treatment strategies and patient care. The PubMed and Embase databases were searched to identify randomized controlled trials comparing levodopa with other anti-Parkinson's drugs published in English before June 31, 2023.
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- The study examines the effectiveness of combining traditional Chinese medicine (TCM) compounds with levodopa in treating Parkinson's disease (PD) to provide evidence-based guidance for clinical use.
- A systematic search of six databases identified 20 high-quality randomized controlled trials, which included 1,784 patients, showing improved outcomes in PD management when TCM was combined with levodopa compared to levodopa alone.
- Data mining identified a basic prescription for treating PD that included specific herbs, notably Paeoniae Radix Alba and Rehmanniae Radix Praeparata, which were linked to significant improvements in various aspects of the Unified Parkinson’s Disease Rating Scale.