Publications by authors named "Taoping Zhang"
Japanese encephalitis virus (JEV), a member of the Flaviviridae family and a flavivirus, is known to induce acute encephalitis. Vimentin protein has been identified as a potential receptor for JEV, engaging in interactions with the viral membrane protein. The Fc fragment, an integral constituent of immunoglobulins, plays a crucial role in antigen recognition by dendritic cells (DCs) or phagocytes, leading to subsequent antigen presentation, cytotoxicity, or phagocytosis.
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- Rabies is a deadly virus that has plagued humans for centuries, with nearly a 100% fatality rate, leading researchers to seek effective vaccines.
- This study involved creating a rabies DNA vaccine by using E. coli to deliver a highly antigenic polypeptide that targets the rabies virus, assembled in a specific expression vector.
- Experimental results showed that the vaccine successfully triggered antibody production in mice and improved their survival when exposed to the virus, suggesting that utilizing food-borne microorganisms as delivery vehicles could be a promising strategy in rabies eradication efforts.
More than 250 million people worldwide have chronic hepatitis B virus (HBV) infections, resulting in over 1 million annual fatalities because HBV cannot be adequately treated with current antivirals. Hepatocellular carcinoma (HCC) risk is elevated in the presence of the HBV. Novel and powerful medications that specifically target the persistent viral components are needed to remove infection.
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