Purification and characterization of Se-enriched Grifola frondosa glycoprotein, and evaluating its amelioration effect on As -induced immune toxicity.

Background: Selenium (Se)-enriched glycoproteins have been a research highlight for the role of both Se and glycoproteins in immunoregulation. Arsenic (As) is a toxicant that is potentially toxic to the immune function and consequently to human health. Several reports suggested that Se could reduce the toxicity of heavy metals.