Bacterial Community Composition and Its Relationship with Environmental Factors in the Artificial Reef Area for Marine Ranching in Changhai County.

In this study, samples were collected from different types of artificial fish reefs and prevention and control areas in the sea areas of the northern part of Da Changshan Island and the northeastern part of Xiao Changshan Island in the North Yellow Sea. The purpose is to compare the differences in the bacterial communities among different regions, determine the impacts of environmental factors on the bacterial communities, and evaluate the ecological effects of artificial fish reefs on the marine bacterial communities. We obtained a total of 2,128,186 effective sequences and 4321 bacterial operational taxonomic units (OTUs), which were classified into 14 phyla and 76 genera.

Insight into the Nature of Nickel Active Sites on the NiAlO Catalyst for Phenanthrene Hydrogenation Saturation.

Hydrogenation saturation of phenanthrene (a typical component of coal tar) could not only improve the combustion performance of fuel oil, but also obtain the raw material for preparing high-energy-density fuel. Nickel-based catalysts have been considered promising catalysts for the hydrogenation saturation of phenanthrene due to their appealing capacity to activate phenanthrene molecules. However, the Ni derivation precursor greatly affects its hydrogenation activity.

Neutrophil extracellular traps license macrophage production of chemokines to facilitate CD8+ T cell infiltration in obstruction-induced renal fibrosis.

Renal fibrosis is a common mechanism leading to kidney failure in chronic kidney diseases (CKDs), including obstructive nephropathy (ON). Dysregulated inflammation is central to the development of renal fibrosis, but how local immune cells within the tissue microenvironment integrate and coordinate to drive this condition remains largely unknown. Herein, we documented that neutrophils were abundantly recruited and expelled neutrophil extracellular traps (NETs) in human and mouse fibrotic kidneys.

Quantitative analysis of peripapillary RNFL capillary density and thickness in patients with mild nonproliferative diabetic retinopathy.

Purpose: Optical coherence tomography angiography was used to compare the changes of capillary density and thickness of the peripapillary retinal nerve fiber layer in patients with diabetes mellitus (DM) without diabetic retinopathy (DR) and patients with mild nonproliferative diabetic retinopathy (NPDR).

Methods: In this prospective cross-sectional study, 62, 85, and 75 eyes of normal control group (NC), DM group, and NPDR group were included, respectively. All subjects received an optic-disc-centered 6 × 6-mm fundus scan.

Ecological stoichiometric characteristics of two dominant macrozoobenthos taxa in Dalian Island, northern Yellow Sea, China.

Macrozoobenthos play a pivotal role in the biogeochemical cycling of C, N, and P in nearshore marine ecosystems by nutrient retention and recycling. To maintain the dynamic equilibrium in elemental contents, zoo-benthos must get a balance with their resource supply or alter their stoichiometric characteristics in response to environmental changes. We investigated the ecological stoichiometric characteristics of six macrozoobenthos species, including bivalve () and ophiuroidea (), which were collected from the coastal waters of Dalian Island in the northern Yellow Sea in May and August 2020.

Safety analysis of brachial artery sheath removal after heparin reversal with a half dose of protamine after percutaneous coronary intervention: a single-center experience.

Aim: To evaluate the safety of brachial artery (BA) sheath removal after heparin neutralization with a half dose of protamine immediately after percutaneous coronary intervention (PCI).

Methods: The clinical data of 209 consecutive patients who underwent PCI through the BA at Fu Wai Hospital between September 2019 and June 2024 were retrospectively collected. In group I, the brachial sheath was removed 4 h after the PCI procedure.

Responses of soil respiration and its temperature sensitivity to nitrogen and phosphorus depositions in a riparian zone.

Nitrogen and phosphorus depositions and global warming have continuously intensified, impacting soil respiration. However, the response mechanisms of soil respiration rate (R) and its temperature sensitivity (Q) to nitrogen and phosphorus depositions are still unclear, especially for riparian zones. Intact Fluvisols were collected at different water-level elevations (150, 160, 170, and 180 m) of the riparian zone of the Three Gorges Reservoir, China and incubated under 20 and 30 °C with additions of nitrogen (36 kg N ha yr), phosphorus (0.

Binding of to dystrophin impairs the membrane trafficking of Nav1.5 protein and increases ventricular arrhythmia susceptibility.

Dystrophin is a critical interacting protein of Nav1.5 that determines its membrane anchoring in cardiomyocytes. Long noncoding RNAs (lncRNAs) are involved in the regulation of cardiac ion channels, while their influence on sodium channels remains unexplored.

RAP1 is essential for PRRSV replication and the synthesis of the viral genome.

Since its emergence, porcine reproductive and respiratory syndrome (PRRS) has caused enormous economic losses to the global swine industry. The pathogenesis of PRRS remains under investigation. The porcine reproductive and respiratory syndrome virus (PRRSV) causes reproductive disorders in pigs and respiratory in piglets, which is a 15 kb RNA virus that encodes 16 viral proteins, most of which exhibit multiple functions during the virus lifecycle.

Comparison of Robot-assisted Laparoscopic Extravesical Ureteral Reimplantation for Primary Vesicoureteral Reflux in Infants Under One Year of Age and Older Children.

Purpose: To assess the surgical outcomes of Robot-Assisted Laparoscopic Extravesical Ureteral Reimplantation (RALUR-EV) in infants under one year of age with primary vesicoureteral reflux (VUR) as compared to older children.

Materials And Methods: A retrospective analysis was conducted on 48 children with VUR who underwent unilateral or bilateral RALUR-EV between June 2018 and December 2022. Patients were divided into two groups: Group A (25 infants under one year) and Group B (23 children over one year).

Idiopathic scrotal calcinosis: Case report and literature review.

Introduction: This case report discusses the clinical manifestations, diagnosis and treatment of idiopathic scrotal calcinosis, and reviews the literature of similar cases, providing important reference for the diagnosis and treatment of this rare disease.

Case Presentation: Idiopathic scrotal calcinosis is a rare condition characterized by calcium deposition in the skin of the scrotum. We present a case of a 67-year-old male patient with idiopathic scrotal calcinosis, a rare condition characterized by calcium deposition in the skin of the scrotum.

Antibiotic residue detection by novel photoelectrochemical extended-gate field-effect transistor sensor.

Residual antibiotics in the environment may pose threats to both ecological system and public health, necessitating the development of efficient analytical strategy for monitoring and control. This study proposes a photoelectrochemical extended-gate field-effect transistor (PEGFET) sensor for specific and sensitive detection of kanamycin. The sensor utilizes ITO glass as the extended gate electrode (photoelectrode) and titanium dioxide as the photosensitive material.

Nomogram for predicting severe abdominal adhesions prior to definitive surgery in patients with anastomotic fistula post-small intestine resection: a cohort study.

Background: This study aimed to develop and validate a nomogram for predicting the presence of severe intra-abdominal adhesions before definitive surgery (DS) for anastomotic fistula following small intestine resection (SIR).

Methods: Patients were enrolled from January 2009 to October 2023 and were randomly divided (2:1) into development and validation cohorts. Predictors of severe adhesion were identified and integrated into a nomogram.

Type-B response regulator RRB12 regulates nodule formation in Lotus japonicus.

Background: The mutualistic beneficial relationship between legume plants and rhizobia enables the growth of plants in nitrogen-limiting conditions. Rhizobia infect legumes through root hairs and trigger nodule organogenesis in the cortex. The plant hormone cytokinin plays a pivotal role in regulating both rhizobial infection and the initiation of nodule development.

Insights on Immobilization of Cd Contamination in Soil: Synergic Impacts of Water Management and Bauxite Residue.

To immobilize the activity and bioavailability of soil Cd, the single treatment only flooding (F) and the combined treatments with flooding plus bauxite residue (F-B) or lime (F-L) were designed to investigate the impacts of different treatments on the toxicity and bioavailability of Cd in contaminated soil. Compared with the single treatment (F), the combined treatments (F-B and F-L) improved soil-associated organic functional groups and aggregated stability in soil. The average particle sizes of soil aggregates increased from 126 nm (F-treated soil) to 256 and 270 nm following F-B and F-L treatments, respectively.

Virus-like particle encapsulation of functional proteins: advances and applications.

Proteins face several challenges in biomedicine, including issues with antibody production, degradation by proteases, rapid clearance by the kidneys, and short half-lives. To address these problems, various nano delivery systems have been developed, with virus-like particles (VLPs) emerging as a leading solution. VLPs, which are self-assembled protein complexes, offer effective encapsulation and transport of proteins.

Invasive aspergillosis complicated in a patient with non-small cell lung cancer harboring fusion during treatment with RET-TKIs: a case report and literature review.

Pralsetinib and selpercatinib have been approved as specific tyrosine kinase inhibitors (TKIs) for the treatment of patients with non-small cell lung cancer (NSCLC) harboring rearranged during transfection () fusion and mutation. However, adverse events associated with pralsetinib and selpercatinib are not fully understood, especially in the real world. In this case, invasive aspergillosis that appeared concurrent with RET-TKI targeted therapy is proposed to be an additional adverse drug reaction (ADR) that was not mentioned in previous reports.

Mechano-regulation of GLP-1 production by Piezo1 in intestinal L cells.

Glucagon-like peptide 1 (GLP-1) is a gut-derived hormone secreted by intestinal L cells and vital for postprandial glycemic control. As open-type enteroendocrine cells, whether L cells can sense mechanical stimuli caused by chyme and thus regulate GLP-1 synthesis and secretion is unexplored. Molecular biology techniques revealed the expression of Piezo1 in intestinal L cells.

Carbon and nitrogen stoichiometry across plant-soil system accounts for the degradation of multi-year alfalfa grassland.

Alfalfa ( L.) grassland is prone to degradation following multi-year maintenance. Yet, its mechanism regarding the stoichiometry of carbon (C) and nitrogen (N) across plant-soil system is still unclear.

Exploring the potential role of microbiota and metabolites in acute exacerbation of chronic obstructive pulmonary disease.

The acute exacerbation of chronic obstructive pulmonary disease seriously affects the respiratory system function and quality of life of patients. This study employed 16S rRNA sequencing and metabolomics techniques to analyze the respiratory microbiota and serum metabolites of COPD and AECOPD patients. The results showed that the microbial diversity in the respiratory tract of AECOPD patients was significantly lower than that of COPD patients, and the relative abundance of Bacteroidetes, and in the respiratory tract of AECOPD patients was significantly lower than that of COPD patients.

[Expression of S100A4 in mast cells and diagnostic values of serum S100A4 in allergic asthma].

Objective To preliminarily investigate the potential involvement of the calcium-binding protein S100A4 in the lipid metabolism of mast cells and its clinical significance in allergic asthma. Methods The allergic asthma-related expression matrix, GSE213085, was downloaded from the GEO database, and the data visualization were visualized by the R package. C57 mast cells were used for further knockdown of S100A4 by lentivirus transfection.