SPS-RCNN: Semantic-Guided Proposal Sampling for 3D Object Detection from LiDAR Point Clouds.

Three-dimensional object detection using LiDAR has attracted significant attention due to its resilience to lighting conditions and ability to capture detailed geometric information. However, existing methods still face challenges, such as a high proportion of background points in the sampled point set and limited accuracy in detecting distant objects. To address these issues, we propose semantic-guided proposal sampling-RCNN (SPS-RCNN), a multi-stage detection framework based on point-voxel fusion.

Use of long peripheral catheters in the infusion therapy of lung cancer patients.

Objective: To investigate the applicability, safety, and efficacy of long peripheral catheters in the infusion therapy of lung cancer patients.

Methods: A retrospective analysis was conducted to examine the baseline data, catheter placement procedures, associated complications, as well as the costs of catheter placement and maintenance among patients who underwent long peripheral catheter insertion in our lung oncology unit from June to December 2023.

Results: The average catheterization time was approximately 20 min, achieving a success rate of 71.

Effect of different head position during tracheal intubation on postoperative sore throat: a randomized clinical trial.

Introduction: Postoperative sore throat is the most frequently complaint after tracheal intubation. We aimed to determine whether changing patients' head position during intubation reduces the incidence of postoperative sore throat.

Methods: We randomized 130 patients receiving oral tracheal intubation into one of the two groups: the sniffing position group and elevation position group.

Modified bFGF targeting connective tissue growth factor in the injured microenvironment improved cardiac repair after chronic myocardial ischemia.

Myocardial infarction (MI) was a cardiovascular emergency that led to heart failure, arrhythmia, and sudden death. Basic fibroblast growth factor (bFGF) was revealed to promote angiogenesis and protect cardiomyocytes against ischemic injury. But conventional delivery of bFGF in an uncontrolled manner was inefficient and diffusive, limiting its application in MI therapy.

Spread of local anaesthetic after erector spinae plane block: a randomised, three-dimensional reconstruction, imaging study.

Background: Spread of local anaesthetic solution in the paravertebral space after erector spinae plane block (ESPB) is variable. We evaluated whether paravertebral spread of local anaesthetic is affected by patient position after ESPB.

Methods: We randomised 84 patients to receive ESPB at T with a mixture of 0.

Efficacy evaluation of a minimally invasive surgical procedure (oblique lateral interbody fusion) for lumbar spinal tuberculosis-retrospective cohort study.

Objective: In the current study, to demonstrate the advantages of oblique lateral interbody fusion (OLIF), we focused on the therapeutics for lumbar spinal tuberculosis with the comparison of three treatments, including anterior approach, posterior approach, and OLIF combined with posterior percutaneous pedicle screw fixation.

Methods: This study included patients with lumbar spinal tuberculosis from July 2015 to June 2018. We divided these patients into three groups: 35 patients underwent an anterior-only approach (Group A), 36 patients underwent a posterior-only approach (Group B), and 31 patients underwent OLIF combined with posterior percutaneous pedicle screw fixation (Group C).

Effect of coexisting nutrient divalent cations on cadmium transport in soil-herbal crop systems.

Cadmium (Cd) pollution in Chinese herbal medicines poses a serious risk to medication safety. Regulating Cd uptake, transport, and accumulation in plants through ion-ion interactions offers a novel, environmentally sustainable, and practical approach to address this issue. However, the effects and underlying mechanisms of coexisting divalent cations zinc (Zn), magnesium (Mg), and manganese (Mn) on Cd uptake by Ligusticum sinense cv.

Utilizing DNA Logic Device for Precise Detection of Circulating Tumor Cells via High Catalytic Activity Au Nanoparticle Anchoring.

As medical advancements turn most cancers into manageable chronic diseases, new challenges arise in cancer recurrence monitoring. Detecting circulating tumor cells (CTCs) is crucial for monitoring cancer recurrence, but the current methods are cumbersome and costly. This study developed a new CTC detection system combining DNA aptamer recognition, hybridization chain reaction (HCR) technology, and DNA logic devices, enabling the one-step recognition of CTCs by identifying multiple membrane proteins.

Photocatalytic Upcycling of Plastic Waste into Syngas by ZnS/GaO Z-Scheme Heterojunction.

The photocatalytic conversion of plastic waste into value-added products using solar energy presents a promising approach for promoting environmental sustainability. Nonetheless, the emission of CO during the conventional photocatalytic degradation process remains a major hurdle that impedes its further development. In this study, we propose an efficient photocatalytic conversion of polyethylene plastic into syngas (CO+H mixtures) by using a ZnS/GaO Z-scheme heterojunction photocatalyst.

A review on the promising antibacterial agents in bone cement-From past to current insights.

Antibacterial bone cements (ABCs), such as antibiotic-loaded bone cements (ALBCs), have been widely utilized in clinical treatments. Currently, bone cements loaded with vancomycin, gentamicin, tobramycin, or clindamycin are approved by the US Food and Drug Administration. However, traditional ALBCs exhibit drawbacks like burst release and bacterial resistance.

Global, regional, and national time trends in the burden of epilepsy, 1990-2019: an age-period-cohort analysis for the global burden of disease 2019 study.

Background: Epilepsy is a non-communicable chronic brain disease that affects all age groups. There are approximately 50 million epilepsy patients worldwide, which is one of the most common neurological disorder. This study reports the time trends in the burden of epilepsy from 1999 to 2019.

Therapeutic potential of Chinese medicinal herbs stimulating osteogenic differentiation of bone marrow-derived mesenchymal stem cells in osteoporosis.

Osteoporosis (OP) is a common and complex chronic metabolic disease with an increasing incidence rate, which has markedly increased the human health burden worldwide. The predominant cause of OP is an imbalance between osteoblasts (OB) and osteoclasts (OC). Studies on the correlation between bone marrow-derived mesenchymal stem cells (BMSCs) and OP have indicated that BMSCs-induced OB differentiation is an important pathway for bone tissue renewal.

Ultrasound-guided superior laryngeal nerve block: a randomized comparison between parasagittal and transverse approach.

Background: Different approach ultrasound-guided superior laryngeal nerve block was used to aid awake intubation, but little is known which approach was superior. We aimed to compare the parasagittal and transverse approaches for ultrasound-guided superior laryngeal nerve block in adult patients undergoing awake intubation.

Methods: Fifty patients with awake orotracheal intubation were randomized to receive either a parasagittal or transverse ultrasound-guided superior laryngeal nerve block.

The Origin and Course of the Blood Supply to the Lower Eyelid Orbital Fat: Anatomical Study and Clinical Significance.

Purpose: The aim of this study is to investigate the origin and course of the orbital fat arterial supply in the lower eyelid using traditional anatomy and three-dimensional computed tomography (CT).

Methods: Twenty-seven cadaver heads were infused with mercury sulfide contrast media through the ophthalmic artery, maxillary artery, transverse facial artery, and facial artery. CT images were obtained after contrast agent injection, three-dimensional CT scans were reconstructed, and the cadaver heads were dissected.

mir-150-5p inhibits the osteogenic differentiation of bone marrow-derived mesenchymal stem cells by targeting irisin to regulate the p38/MAPK signaling pathway.

Purpose: To study the effect of miR-150-5p on the osteogenic differentiation of bone marrow-derived mesenchymal stem cells (BMSCs), and further explore the relationship between its regulatory mechanism and irisin.

Methods: We isolated mouse BMSCs, and induced osteogenic differentiation by osteogenic induction medium. Using qPCR to detect the expression of osteogenic differentiation-related genes, western blot to detect the expression of osteogenic differentiation-related proteins, and luciferase reporter system to verify that FNDC5 is the target of miR-150-5p.

MiR-21-mediated Metabolic Alteration of Cancer-associated Fibroblasts and Its Effect on Pancreatic Cancer Cell Behavior: Retraction.

[This retracts the article DOI: 10.7150/ijbs.22555.

Study on the effect of compound cultivation on the growth feature and active ingredients content of .

We investigated the effects of the complex cultivation of on microbial communities, secretions, yield, and active ingredients, and the mechanism of action between microbial communities, secretions, and growth and development. Neither maize nor soybean was suitable to grow with , but sesame significantly increased salvinone content, the active ingredient of , and Tanshinone IIA, Tanshinone I, and Cryptotanshinone increased by 27.06%, 22.

Down-regulating nuclear factor of activated T cells 1 alleviates cognitive deficits in a mouse model of sepsis-associated encephalopathy, possibly by stimulating hippocampal neurogenesis.

Sepsis-associated encephalopathy (SAE) is a common complication of sepsis, and has been associated with increased morbidity and mortality. Nuclear factor of activated T cells (NFATs) 1, a transcriptional factor that regulates T cell development, activation and differentiation, has been implicated in neuronal plasticity. Here we examined the potential role of NFAT1 in sepsis-associated encephalopathy in mice.

Non-line-of-sight ultraviolet transmission coverage in non-precipitating, foggy, and rainy weather.

Sensitivity to weather conditions is the principal limitation of free-space optical communication. However, for the scattering based ultraviolet (UV) non-line-of-sight (NLOS) communication, the atmospheric scattering effect functions as an attenuation factor and potentially as a performance enhancer. To investigate the UV NLOS transmission coverage under different weather conditions, we employ the Mie Theory in conjunction with classical aerosol and hydrometeor particle models to estimate the absorption coefficient, the scattering coefficient, and the scattering phase function.

Ferroptosis: An Emerging Target for Bladder Cancer Therapy.

Bladder cancer (BC), as one of the main urological cancers in the world, possesses the abilities of multiple-drug resistance and metastasis. However, there remains a significant gap in the understanding and advancement of prognosis and therapeutic strategies for BC. Ferroptosis, a novel type of iron-dependent regulated cell death, depends on lipid peroxidation, which has been proven to have a strong correlation with the development and treatment of BC.

Early life adverse exposures in irritable bowel syndrome: new insights and opportunities.

Irritable bowel syndrome (IBS) is a prevalent functional gastrointestinal disorder worldwide. Extensive research has identified multiple factors contributing to its development, including genetic predisposition, chronic infection, gut dysbiosis, aberrant serotonin metabolism, and brain dysfunction. Recent studies have emphasized the critical role of the early life stage as a susceptibility window for IBS.

Facile synthesis of hierarchical CdS nanoflowers for efficient piezocatalytic hydrogen evolution.

Piezocatalytic hydrogen evolution has emerged as a promising field for the collection and utilization of mechanical energy, as well as for generating sustainable energy throughout the day. Hexagonal CdS, an established semiconductor photocatalyst, has been widely investigated for its ability to split water into H. However, its piezocatalytic performance has received less attention, and the relationship between its structure and piezocatalytic activity remains unclear.

Global, regional, and national time trends in cancer mortality attributable to high fasting plasma glucose: an age-period cohort analysis.

Background: High fasting plasma glucose (HFPG) is the fastest-growing risk factor for cancer deaths worldwide. We reported the cancer mortality attributable to HFPG at global, regional, and national levels over the past three decades and associations with age, period, and birth cohort.

Methods: Data for this study were retrieved from the Global Burden of Disease Study 2019, and we used age-period-cohort modelling to estimate age, cohort and period effects, as well as net drift (overall annual percentage change) and local drift (annual percentage change in each age group).