[Retracted] Limb remote ischemic post‑conditioning reduces injury and improves long‑term behavioral recovery in rats following subarachnoid hemorrhage: Possible involvement of the autophagic process.

Following the publication of the above paper, a concerned reader drew to the attention of the Editorial Office that the 'Sham' brain image featured in Fig. 1B on p. 23 was strikingly similar to an image that was published subsequently in the journal , whereas the control TUNEL assay data shown in Fig.

Genomic Epidemiology of ST81 in Multiple Hospitals in China.

Background: sequence type (ST) 81, mainly associated with ribotype (RT) 369, is a TcdA-negative and TcdB-positive genotype and a common ST found in China. Furthermore, ST81 strains are reported with highest resistance rates to many antimicrobial agents. However, given the potential for ST81 transmission, research into the epidemiological characteristics of this type of ST remain limited.

Chinese guidelines for minimally invasive donor hepatectomy in living donor liver transplantation (2024 edition).

Background: Minimally invasive surgeries are increasingly central to modern medicine, particularly in liver transplantation. These techniques, which offer reduced trauma, precise operations, minimal bleeding, and swift recovery, are, however, unevenly adopted across China. Only a limited number of centers routinely perform minimally invasive donor hepatectomies, indicating a significant imbalance in the development and application of these advanced procedures.

Optimization of a large aperture wedge prism support system based on the closed-loop structural-thermal-optical performance method.

In the instrument suite of the Thirty Meter Telescope (TMT), the linear atmospheric dispersion corrector (LADC) is positioned at the forefront of the spectrometer to mitigate atmospheric dispersion. The LADC comprises two large aperture wedge prisms, each approximately 1.5 meters in diameter.

Modeling of compliant-based support for large aperture rotary prisms with horizontal-axis.

In the Thirty-Meter-Telescope (TMT), a pair of wedge prisms with diameters of approximately 1500 mm are proposed to mitigate atmospheric dispersion across different zenith angles. This is achieved through controlled linear and rotary movements of the prisms. However, providing stable support for such large aperture prisms, with variable cross-sections and capable of rotating 360° around a horizontal optical axis, poses a significant challenge.

Pancreatic cancer tumor organoids exhibit subtype-specific differences in metabolic profiles.

Background: Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive disease characterized by complex metabolic rewiring that enables growth in changing nutrient availability and oxygen conditions. Transcriptome-based prognostic PDAC tumor subtypes, known as 'basal-like' and 'classical' subtypes are associated with differences in metabolic gene expression including genes involved in glycolysis. Tumor subtype-specific metabolism phenotypes may provide new targets for treatment development in PDAC, but their functional relevance has not been fully elucidated.

Retraction Notice to: LncRNA PVT1 promotes tumorigenesis of glioblastoma by recruiting COPS5 to deubiquitinate and stabilize TRIM24.

[This retracts the article DOI: 10.1016/j.omtn.

Ruscogenin Exerts Anxiolytic-Like Effect via Microglial NF-κB/MAPKs/NLRP3 Signaling Pathways in Mouse Model of Chronic Inflammatory Pain.

Long-term inflammation can cause chronic pain and trigger patients' anxiety by sensitizing the central nervous system. However, effective drugs with few side effects for treating chronic pain-induced anxiety are still lacking. The anxiolytic and anti-inflammatory effects of ruscogenin (RUS), an important active compound in Ophiopogon japonicus, were evaluated in a mouse model of chronic inflammatory pain and N9 cells.

In Vivo Thoracic Dorsal Root Ganglia (DRG) Calcium Imaging and ECG Recording for Studying Peripheral Nerve Stimulation.

The dorsal root ganglia (DRG), housing primary sensory neurons, transmit somatosensory and visceral afferent inputs to the dorsal horn of the spinal cord. They play a pivotal role in both physiological and pathological states, including neuropathic and visceral pain. In vivo calcium imaging of DRG enables real-time observation of calcium transients in single units or neuron ensembles.

Dose-Dependent Effects of Botulinum Toxin Type A on Prevention of Postoperative Scars in Various Regions in the Body: A Prospective, Double-Blind Randomized Controlled Trial.

Background: Botulinum toxin type A (BTXA) can improve wound healing and reduce scar formation; however, the exact dose required to prevent postoperative scarring across various anatomical sites remains unclear. This study aimed to investigate the effectiveness and optimal concentrations of BTXA for preventing postoperative scarring across various common surgical sites throughout the body.

Methods: In this prospective randomized controlled trial, 46 patients with benign skin tumors received injections of 1, 2.

Gaseous Object Detection.

Object detection, a fundamental and challenging problem in computer vision, has experienced rapid development due to the effectiveness of deep learning. The current objects to be detected are mostly rigid solid substances with apparent and distinct visual characteristics. In this paper, we endeavor on a scarcely explored task named Gaseous Object Detection (GOD), which is undertaken to explore whether the object detection techniques can be extended from solid substances to gaseous substances.

Application of Dynamic [F]FDG PET/CT Multiparametric Imaging Leads to an Improved Differentiation of Benign and Malignant Lung Lesions.

Purpose: To evaluate the potential of whole-body dynamic (WBD) 2-deoxy-2-[F]fluoro-D-glucose positron emission tomography/computed tomography ([F]FDG PET/CT) multiparametric imaging in the differential diagnosis between benign and malignant lung lesions.

Procedures: We retrospectively analyzed WBD PET/CT scans from patients with lung lesions performed between April 2020 and March 2023. Multiparametric images including standardized uptake value (SUV), metabolic rate (MR) and distribution volume (DV) were visually interpreted and compared.

Clinical characteristics of community-onset Clostridioides difficile infections at a tertiary hospital in mainland China: A fourteen-year (2010-2023) retrospective study.

Background: Clostridioides difficile infection (CDI) is an increasingly common disease in healthcare facilities and community settings. However, there are limited reports of community-onset CDI (CO-CDI) in China.

Methods: We collected diarrheal stool samples from 3885 patients who went to outpatient department or emergency department in a tertiary hospital in China during 2010-2023, analyzed the correlation between patients' basic information and the detection rate of CDI.

Two new diterpenoid alkaloids from the roots of and their cytotoxic activity.

A chemical investigation on the roots of afforded two undescribed C-diterpenoid alkaloids nagarumines D and E ( and ). The structures of the new compounds were elucidated by spectral methods such as 1D and 2D (H-H COSY, HMQC, and HMBC) NMR spectroscopy, as well as HR-ESI-MS. The two isolated alkaloids were tested for cytotoxic activity against five gastric tumor cell lines.

Cytotoxic iridoid glycosides from the leaves of .

A phytochemical investigation on the 80% EtOH extract of the leaves of (Lour.) Merr. resulted into the isolation of three undescribed iridoid glycosides, 10----coumaroyl-(4,6)-3,4-dihydro-3-methylthiopaederoside (), 10---feruloyl-(4,6)-3,4-dihydro-2'--3-paederoside (), and 10---caffeoyl-paederosidic acid ethyl ester ().

Characterization and dynamics of intestinal microbiota in patients with Clostridioides difficile colonization and infection.

Gut microbiota dysbiosis increases the susceptibility to Clostridioides difficile infection (CDI). In this study, we monitored C. difficile colonization (CDC) patients from no CDC status (CDN) to CDC status (CDCp) and CDI patients from asymptomatic status before CDI (PRECDI), CDI status (ONCDI), to asymptomatic status after CDI (POSTCDI).

Evaluating stress and displacement in the craniomandibular complex using Twin Block appliances at varied angles: A finite element study.

Objectives: The objective of this investigation was to assess the stress and displacement pattern of the craniomandibular complex by employing finite element methodology to simulate diverse angulations of inclined planes that are incorporated in the Twin Block appliance.

Methods: A 3D finite element representation was established by use of Cone Beam Computed Tomography (CBCT) scans. This comprehensive structure included craniofacial skeletal components, the articular disc, a posterior disc elastic layer, dental elements, periodontal ligaments, and a Twin Block appliance.

Driving factors of residential demand response for the integration of variable renewable power.

The large-scale integration of renewable power poses great challenges to grid stability. Among flexible resources, demand response (DR) stands out for its advantages in cost and efficiency. To identify key factors influencing DR, this study adopted the modified theory of planned behavior (TPB) to establish the conceptual model.

MiR-143-3p regulates chondrogenic differentiation of synovium derived mesenchymal stem cells under mechanical stress through the BMPR2-Smad signalling pathway by targeting BMPR2.

Background: Mesenchymal stem cells (MSCs) derived from the synovium, known as synovium mesenchymal stem cells (SMSCs), exhibit significant potential for articular cartilage regeneration owing to their capacity for chondrogenic differentiation. However, the microRNAs (miRNAs) governing this process and the associated mechanisms remain unclear. While mechanical stress positively influences chondrogenesis in MSCs, the miRNA-mediated response of SMSCs to mechanical stimuli is not well understood.