Riveting Nucleation Enabled Long Cycling Life Calcium Metal Anodes.

Calcium metal batteries with high capacity and low cost are promising alternatives to Li-ion batteries for large-scale energy storage. However, its development is crucially impeded by the irreversible Ca metal anode, which is highly associated with uncontrollable Ca plating/stripping. Here, we report a new riveting strategy to regulate the nucleation and growth of a Ca metal anode in the 3D structure of a carbon nanotube film (CNF) by introducing in situ-formed Na metal mediators.

Risk transmission and driving factors of virtual water flows from the perspective of China's interregional water-energy-food trade.

Changes in water, energy, and food (WEF) trade patterns may reshape water circulation patterns, leading to potential water supply and demand risks. Analysis of virtual water risk transmission characteristics and driving factors from the perspective of WEF trade is highly important for alleviating the risk of water shortages and promoting the efficient use of resources. In this paper, a set of methods for quantifying risk transmission values is constructed on the basis of China's interregional input-output model, and the key paths of interregional virtual water risk transmission caused by WEF trade are identified using innovative methods.

Popularizing Holistic High-Index Crystal Plane via Nonepitaxial Electrodeposition Toward Hydrogen-Embrittlement-Relieved Zn Anode.

Electrodeposition is promising to fabricate Zn electrodes affording nonepitaxial single-crystal textures. Previous research endeavors focus on achieving Zn(002) faceted deposition, nevertheless, the popularization of a high-index Zn plane with favorable electrochemical activity remains poorly explored. There also exists a deficiency in the assessment of the electrodeposited quality of Zn.

Protocol for in vitro generation of innate lymphoid cells from human embryonic tissues.

Deciphering the origins of innate lymphoid cells (ILCs) is critical for a deeper understanding of innate immunity. Here, we present a protocol for assessing ILC potential of human embryonic resources. We describe steps for identifying lymphoid progenitors in human embryonic tissues, then culturing mature ILCs in vitro, and identifying characteristics and functions of different cultured ILC subsets using cellular indexing of transcriptomes and epitopes (CITE)-sequencing and flow cytometry analysis.

Rare giant epithelioid inflammatory myofibroblastic sarcoma of the abdominal cavity in a child: a case report and review of the literature.

Epithelioid inflammatory myofibroblastic sarcoma (EIMS) is a distinct subtype of inflammatory myofibroblastoma tumor (IMT) that is recognized as a rare malignant tumor characterized by anaplastic lymphoma kinase (ALK) positivity, significant aggressiveness, treatment challenges, and a poor prognosis. We report on the case of an 8-year-old boy presenting with abdominal pain and vomiting. Computed tomography (CT) of the abdomen revealed a large tumor, and the pathology results following a biopsy confirmed the diagnosis of EIMS.

A bibliometric analysis of vaccination against atherosclerosis.

A growing body of research indicates the promising potential of vaccines in both preventing and treating atherosclerosis (AS). To gain a comprehensive understanding of the current research landscape and emerging trends in this field, this study conducted a bibliometric analysis of publications on AS vaccines using the Web of Science Core Collection (WoSCC) database, based on the "bibliometric" R package and VOSviewer software. From 1991 to 2024, a total of 462 publications were identified in the WoSCC.

Localisation of the Infraorbital and Mental Foramen in Orthognathic Surgery: a CBCT Study.

Objective: To establish precise positional references for orthognathic surgery by examining the relative positioning of the infraorbital foramen (IOF) in relation to the anterior nasal spine (ANS) and the mental foramen (MF) in relation to the pogonion (Pog).

Methods: A cohort of 115 patients with CBCT images was randomly selected for analysis. Distances and positional relationships between the IOF and ANS, as well as the MF and Pog, were measured using 3D reconstruction images.

Estimating Leaf Nitrogen Accumulation Considering Vertical Heterogeneity Using Multiangular Unmanned Aerial Vehicle Remote Sensing in Wheat.

The accuracy of leaf nitrogen accumulation (LNA) estimation is often compromised by the vertical heterogeneity of crop nitrogen. In this study, an estimation model of LNA considering vertical heterogeneity of wheat was developed based on unmanned aerial vehicle (UAV) multispectral data and near-ground hyperspectral data, both collected at different view zenith angles (e.g.

Coexisting metabolic dysfunction-associated steatotic liver disease exacerbates in-hospital outcomes in patients with heat stroke.

Purpose: This study aimed to investigate the impact of coexisting metabolic dysfunction-associated steatotic liver disease (MASLD) on in-hospital mortality and organ injury markers in patients with heat stroke (HS).

Approach: HS patients were retrospectively identified between July 1, 2022 and September 30, 2023 at West China Hospital, Sichuan University. Baseline characteristics, such as demographics, initial vital signs, and organ functional indicators were collected.

Selective Electrocatalytic Oxidation of Ammonia by Ru-dpp Complexes Containing Aromatic Nitrogen Donor as Axial Ligand.

Inspired by the rapid growth of Ru-based complexes as molecular ammonia oxidation catalysts, we propose novel Ru-dpp complexes bearing a nitrogen donor as the axial ligand into the ammonia oxidation catalysts family. Herein, a series of Ru-dpp complexes [Ru(-,',″-dpp)(bpy)(L)]·PF (where Hdpp = 2-[5-(pyridin-2-yl)-1-pyrrol-2-yl]pyridine; bpy = 2,2'-bipyridine; L = pyridine (); 4-methylpyridine (); pyrimidine (); isoquinoline ()) containing aromatic nitrogen donor axial ligand are synthesized and fully characterized by NMR, IR, and ESI-MS. The structural analysis displays that dpp as a pincer ligand coordinates to ruthenium, and nitrogen donor L binds to ruthenium at an axial ligand.

Research progress on the role of bypass activation mechanisms in resistance to tyrosine kinase inhibitors in non-small cell lung cancer.

The clinical application of small molecule tyrosine kinase inhibitors (TKIs) has significantly improved the quality of life and prognosis of patients with non-small cell lung cancer (NSCLC) carrying driver genes. However, resistance to TKI treatment is inevitable. Bypass signal activation is one of the important reasons for TKI resistance.

Effects of Replacing Fish Meal with Rubber Seed Cake on Growth, Digestive, Antioxidant and Protein Metabolism of Juvenile Asian Red-Tailed Catfish ().

An 8-week feeding trial was conducted to assess the impact of replacing fish meal (FM) with rubber seed cake (RSC) on growth performance, digestive enzyme activity of the gut, antioxidant capacity and protein metabolism-related parameters of plasma and liver in juvenile Asian red-tailed catfish () with an average body weight of 3.21 g. Four isonitrogenous (41.

Constructing Ru-CoP Lewis Acid-Base Pairs to Prompt Hydrogen Evolution Reaction in Alkaline Seawater Electrolyte.

Seawater electrolysis is an ideal approach to generating green hydrogen. Nevertheless, the sluggish kinetics of water dissociation and the detrimental chlorine chemistry environment are serious obstructions for industrial applications. Herein, constructing unique (Co) Lewis acid and (Ru-P) base pair sites in Ru-CoP decorated on nitrogen and phosphorus co-doped carbon (Ru-CoP/NPC) significantly optimizes the energy barrier of water dissociation and enhances the anti-corrosive ability for alkaline seawater splitting.

Ultrastructural characterization of hippocampal inhibitory synapses under resting and stimulated conditions.

The present study uses electron microscopy to document ultrastructural characteristics of hippocampal GABAergic inhibitory synapses under resting and stimulated conditions in three experimental systems. Synaptic profiles were sampled from stratum pyramidale and radiatum of the CA1 region from (1) perfusion fixed mouse brains, (2) immersion fixed rat organotypic slice cultures, and from (3) rat dissociated hippocampal cultures of mixed cell types. Synapses were stimulated in the brain by a 5 min delay in perfusion fixation to trigger an ischemia-like excitatory condition, and by treating the two culture systems with 90 mM high K for 2-3 min to depolarize the neurons.

Synchronous Modulation of H-bond Interaction and Steric Hindrance via Bio-molecular Additive Screening in Zn Batteries.

In addressing challenges such as side reaction and dendrite formation, electrolyte modification with bio-molecule sugar species has emerged as a promising avenue for Zn anode stabilization. Nevertheless, considering the structural variability of sugar, a comprehensive screening strategy is meaningful yet remains elusive. Herein, we report the usage of sugar additives as a representative of bio-molecules to develop a screening descriptor based on the modulation of the hydrogen bond component and electron transfer kinetics.

Biomimetic polymeric nanoreactors with photooxidation-initiated therapies and reinvigoration of antigen-dependent and antigen-free immunity.

Immune cell-mediated anticancer modalities usually suffer from immune cell exhaustion and limited efficacy in solid tumors. Herein, the oxygen-carrying biomimetic nanoreactors (BNR2(O)) have been developed with photooxidation-driven therapies and antigen-dependent/antigen-free immune reinvigoration against xenograft tumors. The BNR2(O) composes polymeric nanoreactors camouflaged with cancer cell membranes can efficiently target homotypic tumors.

Multiomics profiling of mouse polycystic kidney disease progression at a single-cell resolution.

Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney disease and causes significant morbidity, ultimately leading to kidney failure. PKD pathogenesis is characterized by complex and dynamic alterations in multiple cell types during disease progression, hampering a deeper understanding of disease mechanism and the development of therapeutic approaches. Here, we generate a single-nucleus multimodal atlas of an orthologous mouse PKD model at early, mid, and late timepoints, consisting of 125,434 single-nucleus transcriptomic and epigenetic multiomes.

Age Dependent Integration of Cortical Progenitors Transplanted at the Adult CSF-Brain Interface.

There has been renewed interest in neural transplantation of cells and tissues for brain repair. Recent studies have demonstrated the ability of transplanted neural precursor cells and in vitro grown organoids to mature and locally integrate into host brain neural circuitry. Much effort has focused on how the transplant behaves and functions after the procedure, but the extent to which the host brain can properly innervate the transplant, particularly in the context of aging, is largely unexplored.

Gram-Negative Microflora Dysbiosis Facilitates Tumor Progression and Immune Evasion by Activating the CCL3/CCL5-CCR1-MAPK-PD-L1 Pathway in Esophageal Squamous Cell Carcinoma.

Gram-negative (G-) microflora dysbiosis occurs in multiple digestive tumors and is found to be the dominant microflora in the esophageal squamous cell carcinoma (ESCC) microenvironment. The continuous stimulation of G- bacterium metabolites may cause tumorigenesis and reshape the microimmune environment in ESCC. However, the mechanism of G- bacilli causing immune evasion in ESCC remains underexplored.

Monocytes as an early risk factor for acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.

Acute graft-versus-host disease (aGVHD) is a major complication after allogeneic hematopoietic stem cell transplantation (allo-HSCT) and contributes to high morbidity and mortality. However, our current understanding of the development and progression of aGVHD after allo-HSCT remains limited. To identify the potential biomarkers for the prevention and treatment of aGVHD during the early hematopoietic reconstruction after transplantation, we meticulously performed a comparative analysis of single-cell RNA sequencing data from post-transplant patients with or without aGVHD.

Adverse events related to robotic-assisted knee arthroplasty: a cross-sectional study from the MAUDE database.

Background: Robotic-assisted surgical technique has been clinically available for decades, yet real-world adverse events (AEs) and complications associated with primary knee arthroplasty remain unclear.

Methods: In March 2023, we searched the FDA website and extracted AEs related to robotic assisted knee arthroplasty (RAKA) from the MAUDE database over the past 10 years. The "Brand Name" function queried major robotic platforms, including active and semi-active systems.

Unraveling the Potential Dependence of Active Structures and Reaction Mechanism of Ni-based MOFs Electrocatalysts for Alkaline OER.

Nickel-based metal-organic frameworks (MOFs) with flexible structure units provide a broad platform for designing highly efficient electrocatalysts, especially for alkaline oxygen evolution reaction (OER). However, the stability of MOFs under harsh and dynamic reaction conditions poses significant challenges, resulting in ambiguous structure-activity relationships in MOFs-based OER research. Herein, Ni-benzenedicarboxylic acid-based MOF (NiBDC) is selected as prototypical catalyst to elucidate  its real active sites for OER and reaction pathway under different reaction states.