Synopsis of recent research by authors named "Tanya Trippett"
Tanya Trippett's recent research focuses on the effects of cancer on systemic organ function, with particular attention to liver metabolic dysfunction driven by tumor-derived extracellular vesicles (EVPs). Findings indicate that targeting EVP secretion could potentially reverse these dysfunctions in affected livers.
In a pediatric context, her studies include an analysis of immune biomarkers in tumors responding to atezolizumab therapy, highlighting specific gene expressions associated with patient outcomes, which could inform future immunotherapy approaches.
Trippett also explores novel approaches for targeting pediatric solid tumors, including techniques such as germline sequencing and promising chemotherapy regimens that do not rely on anthracyclines, addressing the need for safer treatment options for vulnerable populations.
