Levels of evidence for the outcome of nonsurgical endodontic treatment.

The purpose of this systematic review was (a) to search for clinical articles pertaining to success and failure of nonsurgical root canal therapy, and (b) to assign levels of evidence to these studies. Electronic and manual searches were conducted to identify studies published between January 1966 and September 2004 with information on the success and failure of nonsurgical root canal therapy. Articles were reviewed and graded for strength of level of evidence (LOE) from one (highest level) to five (lowest level).

Effect of MTAD on the bond strength to enamel and dentin.

The purpose of this study was to compare the effect of MTAD (a mixture of a tetracycline isomer [doxycycline], an acid [citric acid], and a detergent [Tween 80]) and phosphoric acid on the bond strength to enamel and dentin using a conventional OptiBond Solo Plus dentin adhesive system. One hundred flat surfaces (50 enamel/50 dentin) were prepared for bonding. Specimens were embedded in acrylic with the flat surface exposed.

Effect of MTAD on flexural strength and modulus of elasticity of dentin.

The purpose of this study was to evaluate the effect of MTAD on the flexural strength and modulus of elasticity of dentin. Dentin bars were randomly assigned to eight groups treated with various concentrations of NaOCl (5.25%, 2.