Publications by authors named "Tanvi Singla"
Non-alcoholic steatohepatitis (NASH) is emerging as a significant global health concern, characterized by hepatic lipid accumulation, inflammation, and hepatocellular injury. Hepatocytic ballooning, a histological feature of NASH, has gained prominence for its role in disease progression and potential as a therapeutic target. This review provides an overview of the current knowledge regarding hepatocytic ballooning in NASH, highlighting the key molecular and cellular mechanisms implicated in its development.
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- * Postpartum depression is influenced by specific biological and psychosocial factors, with inflammation and hormonal dysfunction being key indicators.
- * Treatment often includes psychotherapy and antidepressants, though there are concerns about side effects, making early identification and intervention essential to minimize impacts on both mother and child.
Background: Substance use disorders (SUDs) are considered to be a major risk factor for cardiovascular disorders (CVDs). In 2019, as per the National Drug Use and Health Survey (NSDUH), 20.4 million American adults suffered from a substance use disorder.
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- - India faced a severe second wave of COVID-19, with challenges managing the disease due to medication shortages; tocilizumab and high-dose steroids have shown efficacy, but their comparison was lacking.
- - This study analyzed 336 patients with severe COVID-19, comparing the effects of intravenous tocilizumab and Methylprednisolone Pulse while both groups received standard care, assessing outcomes after 30 days.
- - Results indicated that although tocilizumab reduced the need for invasive ventilation compared to Methylprednisolone (17% vs. 29%), there was no significant difference in mortality rates after 30 days (36% vs. 34%), suggesting further research is needed.
Objectives: Venous thromboembolism (VTE) is a major cause of mortality and morbidity worldwide. This study describes a real-world scenario of VTE presenting to a tertiary care hospital in India.
Methods: All patients presenting with acute VTE or associated complications from January 2017 to January 2020 were included in the study.