Publications by authors named "Tanver Hasan Riyed"
Article Synopsis
- Rheumatoid arthritis (RA) affects 0.1% to 2.0% of people globally and conventional treatments can have serious side effects, highlighting a need for safer alternatives, particularly from natural sources.
- This study used deep learning to assess 2563 natural compounds for their ability to inhibit the TNF-α protein, which plays a key role in RA inflammation, achieving good prediction performance metrics.
- Four promising compounds—Imperialine, Veratramine, and Gelsemine—were identified as potential natural TNF-α inhibitors after thorough evaluation for drug-likeness and stability, showing low toxicity and effective binding energy results.
