Cerebral oxygenation and perfusion kinetics monitoring of military aircrew at high G using novel fNIRS wearable system.

Introduction: Real-time physiological episode (PE) detection and management in aircrew operating high-performance aircraft (HPA) is crucial for the US Military. This paper addresses the unique challenges posed by high acceleration (G-force) in HPA aircrew and explores the potential of a novel wearable functional near-infrared spectroscopy (fNIRS) system, named NIRSense Aerie, to continuously monitor cerebral oxygenation during high G-force exposure.

Methods: The NIRSense Aerie system is a flight-optimized, wearable fNIRS device designed to monitor tissue oxygenation 13-20 mm below the skin's surface.

Wireless Wearable Electrochemical Sensing Platform with Zero-Power Osmotic Sweat Extraction for Continuous Lactate Monitoring.

Wearable and wireless monitoring of biomarkers such as lactate in sweat can provide a deeper understanding of a subject's metabolic stressors, cardiovascular health, and physiological response to exercise. However, the state-of-the-art wearable and wireless electrochemical systems rely on active sweat released either high-exertion exercise, electrical stimulation (such as iontophoresis requiring electrical power), or chemical stimulation (such as by delivering pilocarpine or carbachol inside skin), to extract sweat under low-perspiring conditions such as at rest. Here, we present a continuous sweat lactate monitoring platform combining a hydrogel for osmotic sweat extraction, with a paper microfluidic channel for facilitating sweat transport and management, a screen-printed electrochemical lactate sensor, and a custom-built wireless wearable potentiostat system.

Preliminary Evaluation of a Solar-Powered Wristband for Continuous Multi-Modal Electrochemical Monitoring.

Continuous, non-invasive wearable measurement of metabolic biomarkers could provide vital insight into patient condition for personalized health and wellness monitoring. We present our efforts towards developing a wearable solar-powered electrochemical platform for multimodal sweat based metabolic monitoring. This wrist-worn wearable system consists of a flexible photovoltaic cell connected to a circuit board containing ultra low power circuitry for sensor data collection, energy harvesting, and wireless data transmission, all integrated into an elastic fabric wristband.

Wearable multiplexed biosensor system toward continuous monitoring of metabolites.

Comprehensive metabolic panels are the most reliable and common methods for monitoring general physiology in clinical healthcare. Translation of this clinical practice to personal health and wellness tracking requires reliable, non-invasive, miniaturized, ambulatory, and inexpensive systems for continuous measurement of biochemical analytes. We report the design and characterization of a wearable system with a flexible sensor array for non-invasive and continuous monitoring of human biochemistry.

Activity-Aware Wearable System for Power-Efficient Prediction of Physiological Responses.

Wearable health monitoring has emerged as a promising solution to the growing need for remote health assessment and growing demand for personalized preventative care and wellness management. Vital signs can be monitored and alerts can be made when anomalies are detected, potentially improving patient outcomes. One major challenge for the use of wearable health devices is their energy efficiency and battery-lifetime, which motivates the recent efforts towards the development of self-powered wearable devices.

An Ultra-miniaturized Near Infrared Spectroscopy System to Assess Sleep Apnea in Children with Down Syndrome.

Down syndrome is one of the health disorders that interferes with regular and healthy sleep. Most children with Down syndrome are referred to a sleep clinic for the assessment of the severity of their apnea. Regular polysomnography based assessment of apnea has been challenging with this sensitive patient population.