Publications by authors named "Tanner Ferrell"
Perioperative dysfunction of the fibrinolytic system may play a role in adverse outcomes for liver transplant recipients. There is a paucity of data describing the potential impact of the postoperative fibrinolytic system on these outcomes. Our objective was to determine whether fibrinolysis resistance (FR), on postoperative day one (POD-1), was associated with early allograft dysfunction (EAD).
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- Persistent ascites (PA) after liver transplant (LT) is a common issue that is linked to platelet count and function.
- A study of 105 LT recipients found that 28% experienced PA, with factors like platelet transfusions and low clot strength contributing to this condition.
- Patients with PA not only stayed longer in the hospital but also had a higher likelihood of suffering from intraabdominal infections.
Background: Infection is a leading cause of morbidity in liver transplant (LT). Considering that the fibrinolytic system is altered in sepsis, we investigated the relationship between fibrinolysis resistance (FR) and post-transplant infection.
Methods: Fibrinolysis was quantified using thrombelastography (TEG) with the addition of tPA to quantify FR.
Introduction: One in four liver transplants (LT) require return to the operating room(R-OR) within 48 h of surgery. We hypothesize that donor, recipient, and intraoperative factors will predict R-OR.
Methods: LT recipients were enrolled in an observational study to measure coagulation with thrombelastography (TEG) were assessed with transplant recipient and donor variables for risk of R-OR.
Introduction: During the anhepatic phase of liver transplantation (LT), fibrinolytic activity increases, since the liver clears tissue plasminogen activator (tPA). We hypothesize that patients who fail to reduce fibrinolytic activity following graft reperfusion will have an increased rate of early allograft dysfunction (EAD).
Methods: Assessment of fibrinolysis in liver transplant recipients was quantified with thrombelastography (TEG) LY30.