Photocatalytic Defluorinative α-Aminoalkylation of Allylic Difluorides.

A photocatalytic process was devised to synthesize monofluoroalkenes via defluorinative functionalization of allylic difluorides. -Alkylanilines are used as precursors to α-aminoalkyl radicals, which undergo regioselective addition to allylic difluorides, and subsequent SET and fluoride elimination produce monofluoroalkenes. C-C bond formation on the aniline is site-selective for the least substituted carbon α to nitrogen.