Newfound features associated with Hennekam Syndrome () complicated with comorbid Waldmann's Disease resulting in Celiac Disease.

Key Clinical Message: Adequate evaluation of patients with Hennekam Syndrome (HS) is challenging for physicians, because of multi-organ involvement and complex pathophysiology. We report the first case in an African American with lymphedema, who developed protein-losing enteropathy (PLE) and was successfully diagnosed with HS from cause-and-effect complications by Waldmann's Disease (WD) and comorbid Celiac Disease (CD).

Abstract: As far as we know, this is the 51st case of HS worldwide and the first one in an African American.