Publications by authors named "Tannaz Goodarzi"

Background/aims: IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis and still constitutes one of the most important causes of end-stage renal disease. Abnormal T cell responses may play a role in IgAN pathogenesis. Co-stimulatory molecules such as cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) are important for naive T cells to initiate and terminate immune responses.

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Background: subsp. the causative agent of bacterial citrus canker, has affected citriculture worldwide. Varieties of means have been used to minimize its devastating effects, but no attention has been given to bacteriocins.

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Article Synopsis
  • The Xanthomonas genus typically cannot produce xanthan gum in lactose-based media due to low β-galactosidase expression.
  • This study discovered that certain natural strains of Xanthomonas citri subsp. citri (Xcc) can utilize lactose as their only carbon source to successfully produce xanthan gum.
  • Among the 210 strains isolated, NIGEBK37 was the most efficient, yielding 14.62 g/l of xanthan gum and showing the highest viscosity of 44,170.66 cP, highlighting the limitations of a commercial Xanthomonas strain in similar conditions.
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Neuromyelitis optica (NMO) is an inflammatory demyelinating disorder of the central nervous system that has been thought to be a severe subtype of multiple sclerosis for a long time. The discovery of aquaporin-4 (AQP4) antibody as a highly specific marker responsible for the pathogenesis of NMO, not only has made a revolutionary pace in establishing a serologic distinction between the two diseases, but it has also classified NMO as an antibody-mediated disorder. Similarly, myasthenia gravis (MG) is a well-known antibody-mediated disorder.

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