Publications by authors named "Tanmay Kanitkar"
Background: Water-associated bacterial infections cause a wide spectrum of disease. Although many of these infections are typically due to human host commensal or spp, water exposure can result in infections with environmental gram negatives such as spp, spp, , and spp (collectively VACS).
Methods: We performed a retrospective analysis of the epidemiology, clinical presentation, and outcomes of deep and superficial infections associated with VACS organisms in our health service between 1 January 2015 and 31 December 2023.
Article Synopsis
- People with HIV (PWH) admitted to ICUs have a higher risk of mortality, with this study analyzing data from 2000-2019 to focus on 1-year post-ICU admission mortality trends.
- Among 221 PWH admitted, 108 died within a year, but the overall 1-year mortality risk decreased by 10% annually, adjusted to 7% when accounting for various factors like age and CD4+ count.
- The findings stress a decline in post-ICU mortality rates over time, indicating a need for further research and ongoing care support for PWH after they're discharged from the hospital.
Article Synopsis
- The study analyzes ICU admission outcomes for people with HIV (PWH) at a UK referral center from 2000 to 2019, highlighting a significant decrease in mortality rates over the years.
- Among 221 PWH, the study found in-ICU mortality at 29% and in-hospital mortality at 38.5%, with lower respiratory tract infections being the most common reason for admission.
- Despite adjustments for various patient factors, mortality rates continued to decline, suggesting improvements in critical care and patient health due to advances in treatment.
Background: Since 2015, we prescribed dolutegravir (DTG)-based two drug regimens (DTG-2DR) for 620 people [total cohort 3133 (19.8%)].
Method: Clinic database search 1 January 15 to 31 October 21.
Article Synopsis
- Late diagnosis of HIV significantly contributes to higher in-ICU mortality rates, with 28% of patients having recent late diagnosis linked to worse health outcomes.
- A study analyzed data from 2000 to 2019, finding that in-ICU mortality was 27%, with those diagnosed late facing a 38% mortality rate compared to 22% for those diagnosed earlier.
- The research indicates that 17.08% of in-ICU deaths are attributable to recent late diagnosis, underlining the need for enhanced HIV testing and earlier diagnosis in healthcare.
Background: COVID-19 is infrequently complicated by bacterial co-infection, but antibiotic prescriptions are common. We used community-acquired pneumonia (CAP) as a benchmark to define the processes that occur in bacterial pulmonary infections, testing the hypothesis that baseline inflammatory markers and their response to antibiotic therapy could distinguish bacterial co-infection from COVID-19.
Methods: Retrospective cohort study of CAP (lobar consolidation on chest radiograph) and COVID-19 (PCR detection of SARS-CoV-2) patients admitted to Royal Free Hospital (RFH) and Barnet Hospital (BH), serving as independent discovery and validation cohorts.
We present a case of ventricular fibrillation (VF) secondary to ischaemia induced by coronary artery spasm. An 82-year-old man initially presented with an out-of-hospital VF arrest. On return of spontaneous circulation (ROSC), he was found to be in fast atrial fibrillation (AF); an invasive coronary angiogram revealed unobstructed coronary arteries.
View Article and Find Full Text PDF16S ribosomal-ribonucleic acid polymerase chain reaction (PCR) and targeted PCR aid microbiological diagnosis in culture-negative clinical samples. Despite routine clinical use, there remains a paucity of data on their effectiveness across a variety of clinical sample types, and cost-effectiveness. In this 4 year multicentre retrospective observational study, all clinical samples referred for 16S PCR and/or targeted PCR from a laboratory network serving seven London hospitals were identified.
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