Publications by authors named "Tanja Seifert"
Article Synopsis
- Researchers studied the impact of mRNA SARS-CoV-2 vaccines on patients with autoimmune liver diseases to see if vaccination worsened their conditions.
- A total of 49 patients with primary biliary cholangitis (PBC), 35 with autoimmune hepatitis (AIH), and 9 with primary sclerosing cholangitis (PSC) were tested for autoantibodies before and after vaccination, with results indicating higher rates of autoantibody positivity in liver disease patients compared to healthcare workers.
- Despite some fluctuations in autoantibody levels following vaccination, the study concluded that mRNA vaccines do not cause significant short-term worsening of autoimmunity in these patients.
Pathogenicity of the Gram-negative bacterium pv. depends on a type III secretion (T3S) system which translocates effector proteins into plant cells. T3S systems are conserved in plant- and animal-pathogenic bacteria and consist of at least nine structural core components, which are designated Sct (secretion and cellular translocation) in animal-pathogenic bacteria.
View Article and Find Full Text PDFThe Gram-negative bacterium Xanthomonas campestris pv. vesicatoria translocates effector proteins via a type III secretion system (T3SS) into eukaryotic cells. The T3SS spans both bacterial membranes and consists of more than 20 proteins, 9 of which are conserved in plant and animal pathogens and constitute the core subunits of the secretion apparatus.
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