Publications by authors named "Tanja D Davidsen"
Proc Natl Acad Sci U S A
September 2004
Article Synopsis
- - The complete genome sequencing of Burkholderia mallei ATCC 23344 reveals important details about its pathogenicity and evolutionary background, especially in light of concerns over its potential use as a biological weapon.
- - The analysis found several virulence factors, confirmed through comparison and testing in a hamster model, indicating how the bacterium causes disease.
- - Additionally, the genome shows significant structural changes and contains a large number of simple sequence repeats, which might lead to antigenic variation, complicating the host's immune response against B. mallei infections.
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