Definition of leukocyte subsets in primate central nervous system by polychromatic flow cytometry.

Haematopoietic immune cell populations play an important role in the pathogenesis of numerous neurological disorders. To better understand the function of resident mononuclear phagocytes and migrating leukocytes in the central nervous system (CNS), the definition of these populations in healthy individuals is crucial. Therefore, the composition of CNS-associated leukocytes, isolated from macaque brain tissue, was assessed using multicolor flow cytometry.