Occupational exposure to low frequency magnetic fields and dementia: a case-control study.

Background: Several studies point to a potential aetiological relevance to dementia of exposure to low-frequency magnetic fields, but the evidence is inconclusive.

Objective: To further examine the relationship between low frequency magnetic fields and dementia.

Methods: From 23 general practices, 195 patients with dementia were recruited.

Insulin effects on CSF norepinephrine and cognition in Alzheimer's disease.

We assessed the effects of induced hyperinsulinemia on plasma and cerebrospinal fluid (CSF) levels of norepinephrine (NE) and on cognition for patients with Alzheimer's disease (AD) and normal older adults. For normal adults, insulin increased plasma and CSF NE levels; also, recall for paraphrased details of a story improved as CSF NE levels increased. Mental control was positively correlated with CSF levels of NE for patients.

Longitudinal study on the relationship between symptomatology of dementia and levels of subjective burden and depression among family caregivers in memory clinic patients.

The objective was to evaluate the course and severity of dementia-related symptoms and their relationship to caregivers' subjective burden and depression over time. Forty-five patients with dementia and their caregivers were followed over a period of 2 years. Patients' cognition, function, and behavioral/psychological symptoms were assessed by the Mini Mental State Examination, Syndrome Kurz Test, Geriatric Depression Screening scale, Instrumental Activities of Daily Living Scale, Physical Self Maintenance Scale, Behavioral Abnormalities in Alzheimer's Disease Rating Scale, and Nurses Observation Scale for Geriatric Patients.

Combination therapy in Alzheimer's disease: a review of current evidence.

Treating dementia has become a major challenge in clinical practice. Presently, acetylcholinesterase inhibitors are the first-line drugs in the treatment of Alzheimer's disease (AD). These options are now complemented by memantine, which is approved for the treatment of moderate-to-severe AD.

No effects of a combination of caregivers support group and memory training/music therapy in dementia patients from a memory clinic population.

Objectives: To evaluate the impact of a combination of caregiver support group and memory training/music therapy in dementia patients on behavioural and psychological symptoms (BPSD) and caregiver burden compared to a control group.

Method: Eighteen patient-carer-dyads in the treatment group and 18 patient-carer-dyads as controls were studied in the setting of a memory clinic of a psychiatric university hospital over a period of 2 years. Controls were matched for age, gender, diagnosis, dementia severity, living arrangement and medication.

Association between the psychosocial network and dementia--a case-control study.

In a case-control study, we investigated the possible etiological relevance to dementia of psychosocial network factors, such as marital status, confidants and close relatives, sports activities, cultural activities, club membership; and education. In 23 general practices we recruited 195 patients with dementia. Of these, 108 were suffering from possible Alzheimer's disease, 59 from possible vascular dementia and 28 from secondary or unclassified dementia.