Publications by authors named "Tanille M Butler"
Article Synopsis
- FABP7 is a type of protein that helps move fatty acids and other similar molecules inside cells, acting like a delivery truck.
- When FABP7 grabs onto a specific fatty acid called DHA, it changes where it goes in the cell, moving to the nucleus and affecting how genes work.
- Scientists study how FABP7 changes shape and functions when it binds to different fatty acids using special techniques, and they found that this binding changes its shape a lot!
Fatty acid-binding proteins (FABPs) are chaperones that facilitate the transport of long-chain fatty acids within the cell and can provide cargo-dependent localization to specific cellular compartments. Understanding the nature of this transport is important because lipid signaling functions are associated with metabolic pathways impacting disease pathologies including cancer, autism, and schizophrenia. FABPs often associate with cell membranes to acquire and deliver their bound cargo as part of transport.
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