Publications by authors named "Tania Portillo"
Objective: Voxelotor, a FDA-approved drug for the treatment of patients with sickle cell disease (SCD), inhibits hemoglobin S (HbS) polymerization and increases total hemoglobin via hemolysis reduction. This drug has shown unique patterns in hemoglobin fractionation, affecting its interpretation. We aimed to evaluate whether these voxelotor-induced changes can be linked to improvement of hemolysis markers in pediatric patients on voxelotor.
View Article and Find Full Text PDFManaging Patient With Coexisting Emphysematous Pyelonephritis And Cystitis.
J Ayub Med Coll Abbottabad
June 2021
Article Synopsis
- Emphysematous pyelonephritis (EPN) is a serious kidney infection characterized by gas production in kidney tissue, which can lead to severe complications, especially when combined with emphysematous cystitis (EC).
- The case study presents a 45-year-old woman who underwent emergency procedures, including percutaneous nephrostomy and placement of a Double J stent, to manage her EPN and EC.
- Despite initial improvement, the patient experienced recurring urinary infections and complications, ultimately resulting in a nephrectomy (removal of the kidney), highlighting the rarity and complexity of this condition.
Increased anterior chamber pressure also known as intraocular pressure can result from conditions such as glaucoma and trauma. The pressure in the anterior chamber is measured using tonometer. Measurement of the intraocular pressure is essential, as it requires immediate medical attention to alleviate pain and to avoid temporary or permanent damage to intraocular structures.
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