Early-Stage Luminal B-like Breast Cancer Exhibits a More Immunosuppressive Tumor Microenvironment than Luminal A-like Breast Cancer.

Background: Breast cancer is a heterogeneous malignant disease with a varying prognosis and is classified into four molecular subtypes. It remains one of the most prevalent cancers globally, with the tumor microenvironment playing a critical role in disease progression and patient outcomes.

Methods: This study evaluated tumor samples from 40 female patients with luminal A and B breast cancer, utilizing flow cytometry to phenotypically characterize the immune cells and tumor cells present within the tumor tissue.

Jumping with control: the interplay between psychological constructs and run-up variability in elite jumpers.

Objectives: The purpose of this study was to examine the relationship between psychological aspects (emotional regulation, self-control, mood states, and perceived stress) and components of run-up variability in horizontal jumps and to conduct comparisons based on sex, events (long jump and triple jump), and contextual situations (training versus competition).

Methods: A total of 10 elite-level athletes (five males and five females) with a mean age of 27.14 (±4.