Publications by authors named "Tania Mara P D Guimaraes"
Article Synopsis
- CD4+ and CD8+ T cells can be divided into different types based on surface markers, and these cells play a crucial role in the immune response to tuberculosis (TB), especially regarding their memory and effector functions.
- Patients with active pulmonary TB show a high proportion of IFN-ɣ+ and TNF-α+ central memory CD4+ T cells, indicating a potential protective response, while having fewer CD8+ T effector lymphocytes, which may lead to a weaker response against the bacteria.
- In contrast, those who have been treated for TB and individuals with latent infections exhibit a stronger response from memory CD4+ and CD8+ T cells, emphasizing the importance of long
Montenegro skin test (MST) represents the main complementary diagnostic test for tegumentary leishmaniases (TL) in endemic regions. Most antigen formulations used for the MST contain thimerosal as preservative. The Food and Drug Administration (FDA), however, recommended reducing or eliminating thimerosal from vaccines and other biological reagents and the Agência Nacional de Vigilância Sanitária (ANVISA) in Brazil, prohibited the use of mercurial compounds in immunobiologicals.
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