Diminished ovarian reserve may have no effect on embryo euploidy: A retrospective cohort study.

Objective: Does an association exist between diminished ovarian reserve (DOR) and embryonic aneuploidy risk in young women of reproductive age?

Methods: This retrospective cohort study included 854 participants treated in the Department of Reproductive Medicine, Women's Hospital of Nanjing Medicine University, Nanjing Maternity and Child Health Care Hospital, from May 2016 to September 2023 for a total of 894 cycles. The relationship between ovarian reserve and embryonic euploidy was evaluated using statistical methods such as generalized estimating equation (GEE) and propensity score matching (PSM).

Results: Despite the higher number of biopsied blastocysts in women with normal ovarian reserve, no significant difference in embryonic aneuploidy rates was observed between DOR women and the control group.