Phenotype of cultured fetal perivascular cells from human placenta studied by scanning electron microscopy.

The phenotype of perivascular placental cells has previously been studied using tissue sections from the fetal villi. The examination of these cells in culture by scanning electron microscopy gives us the opportunity to observe their three-dimensional phenotypes and associations outside their normal constraints. Human umbilical endothelial cells, which have a phenotype comparable to that observed in other studies, seem more flattened in culture than in their usual environment.

Pathogenesis of limb and facial malformations induced by pyrimethamine in the rat.

The temporal sequence of morphological events resulting in limb and face malformations was studied in pyrimethamine (PY) treated female rats, 30 mg/kg of PY in a 10 ml/kg suspension of 0.9% NaCl were administered i.p.

Vascular anomalies and pyrimethamine-induced malformations in the rat.

Pyrimethamine injected into the rat on days 12, 13, and 14 of gestation induces several types of malformations, including limb and facial deformities. These malformations appear in the same location as the hemorrhages and hematomas induced by this substance. In order to visualize the extent of the vascular disorders in the affected areas, a polymerizable substance was injected intravenously into the fetus.

Orthostatic postural activity disorders recorded by statokinesimeter in post-concussional syndromes: oculomoter aspect.

The purpose of this paper is to emphasize the influence of the mesencephalic oculomotor system regulation on orthostatic postural regulation. The body at rest is never immobile but it swings continuosly. The amplitudes and the frequencies of body sway give an indication of the function of the different sensorimotor loops which are involved in body balance.

[Experimental hepatic encephalopathy. The effect of portocaval shunt on the evolution of the anterior hypothalamic neurosecretion in the rat (author's transl)].

The evolution of the anterior hypothalamic neurosecretion is studied in control, sham-operated and portocaval shunt rats. In sham-operated related to control rats, no modification of the anterior hypothalamic neurosecretion is observed. In portocaval shunt rats, the hypothalamic neurosecretion increases.

[Correlation between the brain serotonin and the hypothalamic neuro-secretion in rat (author's transl)].

Parenteral administration of PCPA (200 mg/kg) induces changes in the quantitiy and the distribution of hypothalamic neurosecretion. This action appears very quickly and increases during the 48 hours following the injection. The histologic observations disclose a large accumulation of neurosecretory material in the supraoptic nuclei and in the accessory magnocellular groups of the anterior hypothalamus.