Median nerve electrical stimulation for restoring consciousness in patients with traumatic brain injury: study protocol for a systematic review and meta-analysis.

Introduction: Traumatic brain injury (TBI) is one of the prevalent critical illnesses encountered in clinical practice, often resulting in a spectrum of consciousness disorders among survivors. Prolonged states of impaired consciousness can significantly elevate the susceptibility to complications such as urinary tract infections and pulmonary issues, consequently leading to a compromised prognosis and substantially impacting the quality of life for affected individuals. Clinical studies have reported that median nerve electrical stimulation (MNES) may have a therapeutic effect in the treatment of disorders of consciousness (DOC).

Hyponatremia Is Associated with Mortality in Acute Pancreatitis Patients.

Background: Disorders of serum sodium are common among general patients and are associated with poor outcomes. The prognostic value of serum sodium disorders in patients with acute pancreatitis (AP) has not been studied. We conducted this retrospective study to explore the association between serum sodium levels and the outcomes of patients with AP.

Association of daily health behavior and activity of daily living in older adults in China.

This study aims to describe the activity of daily living (ADL) situation and determine the relationship between health behavior and ADL among older adults in China. A cross-sectional, observational study was conducted in one urban community and one rural community in Chengdu (a city located in Southwest China), China, from October 2022 to March 2023. A total of 706 older adults were included in this study.

Effect of hydrocolloid dressing on pressure ulcer in patients with non-invasive positive pressure ventilation: A meta-analysis.

This study systematically evaluated the effect of hydrocolloid dressings on facial pressure ulcers in patients receiving non-invasive positive pressure ventilation (NIPPV). The Embase, PubMed, Cochrane Library, CNKI, VIP, Chinese Biomedical Literature Database and Wanfang databases were searched for randomised controlled trials on the use of hydrocolloid dressings in patients receiving NIPPV published from the inception of each database to August 2023. The literature was independently screened, data were extracted by two authors based on the inclusion and exclusion criteria, and the quality of the included literature was assessed.

Evaluation of grouped capsule network for intracranial hemorrhage segmentation in CT scans.

Intracranial hemorrhage is a cerebral vascular disease with high mortality. Automotive diagnosing and segmentation of intracranial hemorrhage in Computed Tomography (CT) could assist the neurosurgeon in making treatment plans, which improves the survival rate. In this paper, we design a grouped capsule network named GroupCapsNet to segment the hemorrhage region from a Non-contract CT scan.

Impact of peripherally inserted central venous catheter-associated phlebitis in neonate guided by intracavitary electrocardiogram: A systematic review and meta-analysis of randomised controlled trials.

Because the application of intracavitary electrocardiogram (IC-ECG)-guided peripherally inserted central catheter (PICC) in the treatment of neonates is controversial in terms of phlebitis reduction compared with traditional X-ray positioning technique, a systematical evaluation is needed on the impact of IC-ECG on this common complication following PICC. Literature retrieval was conducted on large databases including PubMed, Google Scholar, Cochrane library, and CNKI. Randomised controlled trials (RTCs) of intracavitary electrocardiogram-guided peripherally inserted central catheter tip placement in the treatment of neonates up to July 7, 2022, were collected.

Resilient bismuthene-graphene architecture for multifunctional energy storage and wearable ionic-type capacitive pressure sensor device.

A facile resilient bismuthine-anchored graphene architecture is reported as multifunctional all-solid-state flexible supercapacitors and ionic-type capacitive sensor. Meanwhile, an electrons/ions dual transport channels design is achieved by inserting elaborately conductive bismuthene flakes into hierarchical porous aerogel framework. This strategy concurrently realizes the expansion of interlayer space for favoring electrolyte infiltration, and boost of interlayer conductivity to ensure interlayer electrons transport, endowing the device with attractive electrochemical energy storage and pressure sensing performance.

Preoperative Hemoglobin Level, Oxygen Saturation and Postoperative Outcomes in Children With Cyanotic Congenital Heart Disease: A Propensity-Score Matching Analysis.

Background: The optimal preoperative hemoglobin (Hb) level is difficult to define in children with cyanotic congenital heart disease (CHD) due to hypoxemia-induced secondary erythrocytosis. This retrospective study integrated preoperative Hb and pulse oxygen saturation (SpO) using the product of Hb × SpO to predict postoperative outcomes in children with cyanotic CHD.

Patients And Methods: Children aged <18 years undergoing cardiac surgery with cyanotic CHD were included.

Tetralogy of fallot in addition to anomalous aortic origin of a coronary artery in a 1-year-old boy: a case report.

Background: Anomalous aortic origin of a coronary artery (AAOCA) is a rare congenital heart disease, characterized by the coronary artery inappropriately originates from the aorta. It is usually classified according to the sinus where the coronary artery arises from, while anomalous origin of the right coronary being the most common type.

Case Presentation: In this case report, we described a rare case of Tetralogy of Fallot (TOF) in a 1-year-old boy, who also had the anomalous right coronary artery that originated from the left coronary sinus without an intramural segment.

Bispecific Antibodies: From Research to Clinical Application.

Bispecific antibodies (BsAbs) are antibodies with two binding sites directed at two different antigens or two different epitopes on the same antigen. The clinical therapeutic effects of BsAbs are superior to those of monoclonal antibodies (MoAbs), with broad applications for tumor immunotherapy as well as for the treatment of other diseases. Recently, with progress in antibody or protein engineering and recombinant DNA technology, various platforms for generating different types of BsAbs based on novel strategies, for various uses, have been established.

Surgical retrieval of PICC-related right atrial thrombus in a child with acute lymphoblastic leukemia: a case report.

Background: Peripherally inserted central catheters (PICCs) are widely used in cancer patients for administering chemotherapy drugs, antibiotics, and nutrients. PICC-related thrombi are not uncommon and may result in pulmonary embolism and the formation of thrombi in the right atrium. The latter are associated with an increased risk of subsequent morbidity or mortality because of their potential for embolization in the pulmonary vasculature.

The Effect of Diagnostic Blood Loss on Anemia and Transfusion Among Postoperative Patients With Congenital Heart Disease in a Pediatric Intensive Care Unit.

Purpose: To evaluate whether diagnostic blood loss can lead to anemia and consequent blood transfusion among postoperative patients with congenital heart disease (CHD) in the pediatric intensive care unit (PICU).

Design And Methods: This prospective observational study was conducted in a university-affiliated tertiary hospital between January and August 2016. CHD patients aged <12years, undergoing cardiac surgery, with a PICU stay >48h were included (n=205).

Midterm outcome after surgical correction of anomalous left coronary artery from the pulmonary artery.

Background: This study was undertaken to determine the midterm outcome in patients with anomalous left coronary artery from the pulmonary artery (ALCAPA) undergoing coronary reimplantation and Takeuchi repair.

Methods: A retrospective review of patients who had ALCAPA repair between January 2009 and December 2015. Mortality, echocardiography assessment of left ventricular function including ejection fractionand, shortening fraction, severity of mitral regurgitation, stenosis of the coronary ostium were studied retrospectively.

A novel minimal invasive mouse model of extracorporeal circulation.

Extracorporeal circulation (ECC) is necessary for conventional cardiac surgery and life support, but it often triggers systemic inflammation that can significantly damage tissue. Studies of ECC have been limited to large animals because of the complexity of the surgical procedures involved, which has hampered detailed understanding of ECC-induced injury. Here we describe a minimally invasive mouse model of ECC that may allow more extensive mechanistic studies.

Rare association of pulmonary artery sling with tracheo-oesophageal fistula and patent ductus arteriosus.

Congenital tracheo-oesophageal fistula (TEF) is a life-threatening complication caused by communication between the oesophagus and the tracheobronchial tree within the neck or the thorax. TEF without oesophageal atresia is commonly known as 'H'-type TEF, and it is extremely rare in infants, accounting for ∼2-4% of all congenital tracheo-oesophageal malformations. Here, we report a rare case of a pulmonary artery sling with TEF and patent ductus arteriosus.

Airway bacterial colonization in patients with non-small cell lung cancer and the alterations during the perioperative period.

Background: To observe the alterations in airway bacterial colonization during the perioperative period in patients with non-small cell lung cancer (NSCLC) and evaluate their clinical implications.

Methods: Patients with resectable primary NSCLC were enrolled from October 2011 to April 2012. Airway secretions were harvested for microbiological study after admission, immediately after surgery, and before endotracheal extubation.

Closed blood conservation device for reducing catheter-related infections in children after cardiac surgery.

Background: Arterial catheters are potential sources of nosocomial infection.

Objective: To investigate use of a closed blood conservation device in preventing catheter-related bloodstream infections in children after cardiac surgery.

Methods: Children with an indwelling arterial catheter after cardiac surgery were randomly assigned to 2 groups: a control group with a conventional 3-way stopcock in the catheter system and an interventional group with the conservation device in the catheter system.

[Application of peripherally inserted central catheter for parenteral nutrition in critically ill neonates].

Objective: To apply peripherally inserted central catheter (PICC) in critically ill neonates who require long-term parenteral nutrition.

Methods: A retrospective review of 98 critically ill neonates who had a PICC inserted and received long-term parenteral nutrition from March to December 2011 was performed.

Results: The PICC insertion succeeded in 74.