Fatality after cardiac arrest in thyrotoxic periodic paralysis due to profound hypokalemia resulting from intravenous glucose administration and inadequate potassium replacement.

Background: Thyrotoxic periodic paralysis (TPP) is a variant of periodic paralysis (PP) that occurs in patients with underlying mutations in genes for cation channels, if they develop thyrotoxicosis. It is disabling, and fatalities sometimes occur. Here, we present a patient with TPP who developed hypokalemic paralysis that was probably aggravated by the administration of a carbohydrate, probably contributing to, if not causing, a fatal outcome.

Striving for euthyroidism in radioiodine therapy of Graves' disease: a 12-year prospective, randomized, open-label blinded end point study.

Background: In China, use of radioiodine therapy is problematic because of the need for lifelong levothyroxine substitution. Our aim was to find an optimum dosing strategy for (131)I treatment of hyperthyroidism due to Graves' disease (GD). We attempted to achieve euthyroidism to avoid long-term levothyroxine treatment.

Comparison of the long-term efficacy of low dose 131I versus antithyroid drugs in the treatment of hyperthyroidism.

Objective: In China the therapeutic options to treat hyperthyroidism comprise antithyroid drugs (ATDs), radioiodine (131I) therapy and surgery. Physicians in China avoid the risk of hypothyroidism as a consequence of either treatment because patients from rural districts cannot easily comply with long-term medication. Therefore, we prospectively assessed the efficacy and safety of 131I versus ATDs.

[Comparison of the effectiveness of 131-I and antithyroid drugs in the treatment of Graves' disease in children].

Objective: To comprehensively evaluate the treatment of Graves' disease in children with (131)I and antithyroid drugs (ATD) and to quantitatively assess the advantages and disadvantages of them.

Methods: The authors examined the outcome of (131)I and ATD treatment in children with Graves' disease at the Hospital of Dongshan District in Guangzhou during the period 1997 to 2002. Each of the 2 groups of patients consisted of 40 patients ranging in age from 8 to 14 years (mean 10.