Development of S-penthiopyrad for bioactivity improvement and risk reduction from the systemic evaluation at the enantiomeric level.

For the purpose of screening high-efficiency and low-risk green pesticides, a systematic study on fungicide penthiopyrad was conducted at the enantiomeric level. The bioactivity of S-(+)-penthiopyrad (median effective concentration (EC), 0.035 mg/L) against Rhizoctonia solani was 988 times higher than R-(-)-penthiopyrad (EC, 34.

Enantioselective Behaviors of Chiral Fungicide Penthiopyrad in Five Kinds of Crops and Whole-Age Dietary Risk Assessments.

Penthiopyrad is a widely used succinic dehydrogenase inhibitor fungicide with two enantiomers, while the data on its enantioselective behaviors in crops are limited. The enantioselective dissipation may directly or indirectly expose people to the preferentially residual enantiomer, which may affect the dietary risks of chiral penthiopyrad. In this study, the enantioselective behaviors of chiral penthiopyrad in five kinds of crops and whole-age dietary risk assessments were conducted.