Publications by authors named "Tandy Paarlberg"

Article Synopsis
  • Credelio™ (lotilaner) is effective for treating flea and tick infestations in cats, with a single oral dose of 6-24 mg/kg evaluated in this study.* -
  • The study involved two groups of cats: one treated with lotilaner and a control group, with significant reductions in adult fleas and flea egg production observed in the lotilaner group compared to controls.* -
  • Lotilaner was well-tolerated, leading to a high efficacy rate in flea elimination, as nearly all adult fleas were killed within 24 hours, with minimal adverse effects noted.*
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Article Synopsis
  • - The study evaluated the efficacy and safety of lotilaner (Credelio™ CAT) for flea control in cats, finding that it provided a significantly higher flea kill rate compared to fipronil + S-methoprene over a 90-day duration.
  • - A total of 343 cats across 11 veterinary clinics participated, with treatments administered on days 0, 30, and 60, and flea counts measured at multiple intervals.
  • - Results revealed that 98.3% of lotilaner-treated cats were flea-free by day 90, while only 28.8% of those on the fipronil + S-methoprene treatment were flea-free, indicating lotilaner's superior
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Background: A spot-on spinetoram formulation (Cheristin) was developed to eliminate fleas from infested cats. This paper describes three spinetoram studies: two for registration (Studies 1 and 2), and one comparing residual speed of kill (SOK) with topically applied fipronil/(S)-methoprene (FSM) and imidacloprid (Study 3).

Methods: Cats were randomized to treatment based on flea counts from infestations placed within 2 weeks prior to treatment.

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Objective: To compare safety and efficacy of spinosad and selamectin and determine effects of those products on flea allergy dermatitis (FAD) in cats.

Design: Randomized clinical trial. Animals-211 client-owned cats.

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The efficacy of spinosad against adult fleas (Ctenocephalides felis) on dogs was evaluated in three controlled, blinded studies. One study was conducted to determine speed of kill on experimentally infested dogs. Two additional studies were designed to assess the efficacy of spinosad in preventing environmental contamination with flea eggs (USA study and EU study).

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